Assembly of the WHIP-TRIM14-PPP6C Mitochondrial Complex Promotes RIG-I-Mediated Antiviral Signaling.

Tan, Peng; He, Lian; Cui, Jun; Qian, Chen; Cao, Xin; Lin, Meng; Zhu, Qingyuan; Li, Yinyin; Xing, Changsheng; Yu, Xiao; Wang, Helen Y; Wang, Rong-Fu

Tan, Peng; He, Lian; Cui, Jun; Qian, Chen; Cao, Xin; Lin, Meng; Zhu, Qingyuan; Li, Yinyin; Xing, Changsheng; Yu, Xiao; Wang, Helen Y; Wang, Rong-Fu.

Afiliação

Tan P; Institute of Biosciences and Technology, College of Medicine, Texas A&M University, Houston, TX 77030, USA; Center for Inflammation and Epigenetics, Houston Methodist Research Institute, Houston, TX 77030, USA.
He L; Institute of Biosciences and Technology, College of Medicine, Texas A&M University, Houston, TX 77030, USA.
Cui J; Key Laboratory of Gene Engineering of the Ministry of Education, State Key Laboratory of Biocontrol, College of Life Sciences, Collaborative Innovation Center of Cancer Medicine, Sun Yat-sen University, Guangzhou 510275, China.
Qian C; Center for Inflammation and Epigenetics, Houston Methodist Research Institute, Houston, TX 77030, USA.
Cao X; Center for Inflammation and Epigenetics, Houston Methodist Research Institute, Houston, TX 77030, USA.
Lin M; Center for Inflammation and Epigenetics, Houston Methodist Research Institute, Houston, TX 77030, USA.
Zhu Q; Center for Inflammation and Epigenetics, Houston Methodist Research Institute, Houston, TX 77030, USA.
Li Y; Institute of Biosciences and Technology, College of Medicine, Texas A&M University, Houston, TX 77030, USA; Center for Inflammation and Epigenetics, Houston Methodist Research Institute, Houston, TX 77030, USA.
Xing C; Center for Inflammation and Epigenetics, Houston Methodist Research Institute, Houston, TX 77030, USA.
Yu X; Center for Inflammation and Epigenetics, Houston Methodist Research Institute, Houston, TX 77030, USA.
Wang HY; Center for Inflammation and Epigenetics, Houston Methodist Research Institute, Houston, TX 77030, USA. Electronic address: ywang4@houstonmethodist.org.
Wang RF; Institute of Biosciences and Technology, College of Medicine, Texas A&M University, Houston, TX 77030, USA; Center for Inflammation and Epigenetics, Houston Methodist Research Institute, Houston, TX 77030, USA; Department of Microbiology and Immunology, Weill Cornell Medical College, Cornell Uni

Mol Cell ; 68(2): 293-307.e5, 2017 Oct 19.

Article em En | MEDLINE | ID: mdl-29053956

Assuntos

Proteínas de Transporte/imunologia; Proteína DEAD-box 58/imunologia; Proteínas de Ligação a DNA/imunologia; Imunidade Inata; Mitocôndrias/imunologia; Proteínas Mitocondriais/imunologia; Complexos Multiproteicos/imunologia; Fosfoproteínas Fosfatases/imunologia; Transdução de Sinais/imunologia; ATPases Associadas a Diversas Atividades Celulares; Animais; Proteínas de Transporte/genética; Linhagem Celular Tumoral; Chlorocebus aethiops; Proteína DEAD-box 58/genética; Proteínas de Ligação a DNA/genética; Humanos; Peptídeos e Proteínas de Sinalização Intracelular; Mitocôndrias/genética; Proteínas Mitocondriais/genética; Complexos Multiproteicos/genética; Fosfoproteínas Fosfatases/genética; Receptores Imunológicos; Transdução de Sinais/genética; Proteínas com Motivo Tripartido; Células Vero; Viroses/genética; Viroses/imunologia; Vírus/genética; Vírus/imunologia

Palavras-chave

ATPase domain; K63 ubiquitination; RIG-I-like receptor signaling; dephosphorylation; mitochondrial signalosome; ubiquitin binding

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Proteínas de Transporte / Fosfoproteínas Fosfatases / Proteínas Mitocondriais / Complexos Multiproteicos / Proteínas de Ligação a DNA / Proteína DEAD-box 58 / Imunidade Inata / Mitocôndrias Limite: Animals / Humans Idioma: En Revista: Mol Cell Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google