Components in Plasma-Derived Factor VIII, But Not in Recombinant Factor VIII Downregulate Anti-Inflammatory Surface Marker CD163 in Human Macrophages through Release of CXCL4 (Platelet Factor 4).

Bertling, Anne; Brodde, Martin F; Visser, Mayken; Treffon, Janina; Fennen, Michelle; Fender, Anke C; Kelsch, Reinhard; Kehrel, Beate E

Bertling, Anne; Brodde, Martin F; Visser, Mayken; Treffon, Janina; Fennen, Michelle; Fender, Anke C; Kelsch, Reinhard; Kehrel, Beate E.

Afiliação

Bertling A; Department of Anesthesiology, Intensive Care and Pain Medicine, Experimental and Clinical Hemostasis, University of Münster, Münster, Germany.
Brodde MF; Department of Anesthesiology, Intensive Care and Pain Medicine, Experimental and Clinical Hemostasis, University of Münster, Münster, Germany.
Visser M; OxProtect GmbH, Münster, Germany.
Treffon J; Department of Anesthesiology, Intensive Care and Pain Medicine, Experimental and Clinical Hemostasis, University of Münster, Münster, Germany.
Fennen M; Department of Anesthesiology, Intensive Care and Pain Medicine, Experimental and Clinical Hemostasis, University of Münster, Münster, Germany.
Fender AC; Department of Anesthesiology, Intensive Care and Pain Medicine, Experimental and Clinical Hemostasis, University of Münster, Münster, Germany.
Kelsch R; Institute of Pharmacology and Clinical Pharmacology, Heinrich-Heine-University, Düsseldorf, Germany.
Kehrel BE; Institute of Transfusion Medicine and Transplantation Immunology, University Hospital Münster, Münster, Germany.

Transfus Med Hemother ; 44(5): 351-357, 2017 Sep.

Article em En | MEDLINE | ID: mdl-29070980

Palavras-chave

Factor VIII; Hemophilia A; Macrophages; Platelets; Scavenger receptors

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Transfus Med Hemother Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Alemanha

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