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Overcoming the Lack of Oral Availability of Cyclic Hexapeptides: Design of a Selective and Orally Available Ligand for the Integrin αvß3.
Weinmüller, Michael; Rechenmacher, Florian; Kiran Marelli, Udaya; Reichart, Florian; Kapp, Tobias G; Räder, Andreas F B; Di Leva, Francesco Saverio; Marinelli, Luciana; Novellino, Ettore; Muñoz-Félix, José M; Hodivala-Dilke, Kairbaan; Schumacher, Adi; Fanous, Joseph; Gilon, Chaim; Hoffman, Amnon; Kessler, Horst.
Afiliação
  • Weinmüller M; Institute for Advanced Study and Center of Integrated Protein Science, Department Chemie, Technische Universität München, Lichtenbergstrasse 4, 85748, Garching, Germany.
  • Rechenmacher F; Institute for Advanced Study and Center of Integrated Protein Science, Department Chemie, Technische Universität München, Lichtenbergstrasse 4, 85748, Garching, Germany.
  • Kiran Marelli U; Central NMR Facility and Division of Organic Chemistry, CSIR-National Chemical Laboratory, Pune, India.
  • Reichart F; Institute for Advanced Study and Center of Integrated Protein Science, Department Chemie, Technische Universität München, Lichtenbergstrasse 4, 85748, Garching, Germany.
  • Kapp TG; Institute for Advanced Study and Center of Integrated Protein Science, Department Chemie, Technische Universität München, Lichtenbergstrasse 4, 85748, Garching, Germany.
  • Räder AFB; Institute for Advanced Study and Center of Integrated Protein Science, Department Chemie, Technische Universität München, Lichtenbergstrasse 4, 85748, Garching, Germany.
  • Di Leva FS; Dipartimento di Farmacia, Università di Napoli Federico II, Napoli, Italy.
  • Marinelli L; Dipartimento di Farmacia, Università di Napoli Federico II, Napoli, Italy.
  • Novellino E; Dipartimento di Farmacia, Università di Napoli Federico II, Napoli, Italy.
  • Muñoz-Félix JM; Centre for Tumour Biology, Barts Cancer Institute, -, Queen Mary University of London, John Vane Science Centre, Londonn, UK.
  • Hodivala-Dilke K; Centre for Tumour Biology, Barts Cancer Institute, -, Queen Mary University of London, John Vane Science Centre, Londonn, UK.
  • Schumacher A; Institutes of Chemistry and Drug Research, The Hebrew University of Jerusalem, Israel.
  • Fanous J; Institutes of Chemistry and Drug Research, The Hebrew University of Jerusalem, Israel.
  • Gilon C; Institutes of Chemistry and Drug Research, The Hebrew University of Jerusalem, Israel.
  • Hoffman A; Institutes of Chemistry and Drug Research, The Hebrew University of Jerusalem, Israel.
  • Kessler H; Institute for Advanced Study and Center of Integrated Protein Science, Department Chemie, Technische Universität München, Lichtenbergstrasse 4, 85748, Garching, Germany.
Angew Chem Int Ed Engl ; 56(51): 16405-16409, 2017 12 18.
Article em En | MEDLINE | ID: mdl-29072809
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos Cíclicos / Desenho de Fármacos / Integrina alfaVbeta3 Limite: Animals / Humans Idioma: En Revista: Angew Chem Int Ed Engl Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos Cíclicos / Desenho de Fármacos / Integrina alfaVbeta3 Limite: Animals / Humans Idioma: En Revista: Angew Chem Int Ed Engl Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Alemanha