Multigenerational silencing dynamics control cell aging.

Li, Yang; Jin, Meng; O'Laughlin, Richard; Bittihn, Philip; Tsimring, Lev S; Pillus, Lorraine; Hasty, Jeff; Hao, Nan

Li, Yang; Jin, Meng; O'Laughlin, Richard; Bittihn, Philip; Tsimring, Lev S; Pillus, Lorraine; Hasty, Jeff; Hao, Nan.

Afiliação

Li Y; Section of Molecular Biology, Division of Biological Sciences, University of California, San Diego, La Jolla, CA 92093.
Jin M; BioCircuits Institute, University of California, San Diego, La Jolla, CA 92093.
O'Laughlin R; The San Diego Center for Systems Biology, La Jolla, CA 92093.
Bittihn P; Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093.
Tsimring LS; BioCircuits Institute, University of California, San Diego, La Jolla, CA 92093.
Pillus L; The San Diego Center for Systems Biology, La Jolla, CA 92093.
Hasty J; BioCircuits Institute, University of California, San Diego, La Jolla, CA 92093.
Hao N; The San Diego Center for Systems Biology, La Jolla, CA 92093.

Proc Natl Acad Sci U S A ; 114(42): 11253-11258, 2017 10 17.

Article em En | MEDLINE | ID: mdl-29073021

Assuntos

Senescência Celular; Heterocromatina/fisiologia; Microfluídica; Modelos Biológicos; Saccharomyces cerevisiae; Análise de Célula Única

Palavras-chave

chromatin silencing; computational modeling; microfluidics; replicative aging; single-cell analysis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Senescência Celular Tipo de estudo: Prognostic_studies Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2017 Tipo de documento: Article

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