Operative and Therapeutic Advancements in Breast Cancer Metastases to the Brain.
Clin Breast Cancer
; 18(4): e455-e467, 2018 08.
Article
em En
| MEDLINE
| ID: mdl-29100727
ABSTRACT
Patients with breast cancer are surviving longer as the state of the art for care advances. Because patients are surviving longer with primary breast cancer, the incidence of secondary metastatic disease has risen. Metastatic breast cancer to the brain was once thought to be universally fatal. While it is still quite lethal, its treatment after diagnosis is increasingly safe and effective. Critical progress has been made in understanding the interaction between breast metastases and the neural niche, neuroimaging of functional anatomy, minimally invasive image-guided brain surgery, characterizing subtypes of breast cancer based on molecular and genetic profiles, and individualized pharmaceuticals and immunotherapies. In this review, we discuss recent advances that have brought us to state-of-the-art management of metastatic breast cancer to the brain.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Encéfalo
/
Neoplasias Encefálicas
/
Neoplasias da Mama
Tipo de estudo:
Incidence_studies
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Prognostic_studies
Limite:
Female
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Humans
Idioma:
En
Revista:
Clin Breast Cancer
Assunto da revista:
NEOPLASIAS
Ano de publicação:
2018
Tipo de documento:
Article