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Assessing single-stranded oligonucleotide drug-induced effects in vitro reveals key risk factors for thrombocytopenia.
Sewing, Sabine; Roth, Adrian B; Winter, Michael; Dieckmann, Andreas; Bertinetti-Lapatki, Cristina; Tessier, Yann; McGinnis, Claudia; Huber, Sylwia; Koller, Erich; Ploix, Corinne; Reed, John C; Singer, Thomas; Rothfuss, Andreas.
Afiliação
  • Sewing S; Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.
  • Roth AB; Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.
  • Winter M; Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.
  • Dieckmann A; Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.
  • Bertinetti-Lapatki C; Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.
  • Tessier Y; Roche Pharma Research and Early Development, Roche Innovation Center Copenhagen A/S, Hørsholm, Denmark.
  • McGinnis C; Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.
  • Huber S; Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.
  • Koller E; Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.
  • Ploix C; Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.
  • Reed JC; Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.
  • Singer T; Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.
  • Rothfuss A; Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.
PLoS One ; 12(11): e0187574, 2017.
Article em En | MEDLINE | ID: mdl-29107969
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oligonucleotídeos / Trombocitopenia Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Suíça
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oligonucleotídeos / Trombocitopenia Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Suíça