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PINK1-mediated phosphorylation of LETM1 regulates mitochondrial calcium transport and protects neurons against mitochondrial stress.
Huang, En; Qu, Dianbo; Huang, Tianwen; Rizzi, Nicoletta; Boonying, Wassamon; Krolak, Dorothy; Ciana, Paolo; Woulfe, John; Klein, Christine; Slack, Ruth S; Figeys, Daniel; Park, David S.
Afiliação
  • Huang E; University of Ottawa Brain and Mind Research Institute, Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, Canada, K1H 8M5.
  • Qu D; University of Ottawa Brain and Mind Research Institute, Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, Canada, K1H 8M5.
  • Huang T; University of Ottawa Brain and Mind Research Institute, Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, Canada, K1H 8M5.
  • Rizzi N; Center of Excellence on Neurodegenerative Diseases, Department of Pharmacological Sciences, University of Milan, Via Balzaretti 9, 20133, Milan, Italy.
  • Boonying W; University of Ottawa Brain and Mind Research Institute, Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, Canada, K1H 8M5.
  • Krolak D; University of Ottawa Brain and Mind Research Institute, Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, Canada, K1H 8M5.
  • Ciana P; Center of Excellence on Neurodegenerative Diseases, Department of Oncology and Hemato-Oncology, University of Milan, Via Balzaretti 9, 20133, Milan, Italy.
  • Woulfe J; Centre for Cancer Therapeutics, Ottawa Hospital Research Institute and Department of Pathology and Laboratory Medicine, University of Ottawa, Ottawa, ON, Canada, K1H 8M5.
  • Klein C; Institute of Neurogenetics, University of Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Germany.
  • Slack RS; University of Ottawa Brain and Mind Research Institute, Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, Canada, K1H 8M5.
  • Figeys D; Department of Biochemistry, Microbiology and Immunology, Department of Chemistry and Biomolecular Sciences, and Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, ON, Canada, K1H 8M5.
  • Park DS; University of Ottawa Brain and Mind Research Institute, Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, Canada, K1H 8M5. dpark@uottawa.ca.
Nat Commun ; 8(1): 1399, 2017 11 09.
Article em En | MEDLINE | ID: mdl-29123128
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Proteínas Quinases / Proteínas de Ligação ao Cálcio / Cálcio / Proteínas de Transporte de Cátions / Mitocôndrias Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Proteínas Quinases / Proteínas de Ligação ao Cálcio / Cálcio / Proteínas de Transporte de Cátions / Mitocôndrias Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2017 Tipo de documento: Article