Progressive multifocal leukoencephalopathy in the absence of immunosuppression.
J Neurovirol
; 24(1): 119-122, 2018 02.
Article
em En
| MEDLINE
| ID: mdl-29139004
ABSTRACT
A 69-year-old woman presented with a cortical hand syndrome progressing over several weeks. MRI brain showed characteristic appearances of progressive multifocal leukoencephalopathy (PML), confirmed by detection of the JC virus in CSF, despite the absence of any evidence of immunosuppression. Treatment with mirtazapine, mefloquine and cidofovir did not affect the progression of the disease, which was fatal within 7 months of presentation. This report adds to the small case literature that suggests that PML can occur in immunocompetent people, albeit extremely rarely.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Leucoencefalopatia Multifocal Progressiva
/
Vírus JC
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Fenômeno do Membro Alienígena
Limite:
Aged
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Female
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Humans
Idioma:
En
Revista:
J Neurovirol
Assunto da revista:
NEUROLOGIA
/
VIROLOGIA
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Reino Unido