The evolutionary conservation of the bidirectional activity of the NWC gene promoter in jawed vertebrates and the domestication of the RAG transposon.

Sniezewski, Lukasz; Janik, Sylwia; Laszkiewicz, Agnieszka; Majkowski, Michal; Kisielow, Pawel; Cebrat, Malgorzata

Sniezewski, Lukasz; Janik, Sylwia; Laszkiewicz, Agnieszka; Majkowski, Michal; Kisielow, Pawel; Cebrat, Malgorzata.

Afiliação

Sniezewski L; Laboratory of Molecular and Cellular Immunology, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Weigla 12, 53-114 Wroclaw, Poland.
Janik S; Laboratory of Molecular and Cellular Immunology, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Weigla 12, 53-114 Wroclaw, Poland.
Laszkiewicz A; Laboratory of Molecular and Cellular Immunology, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Weigla 12, 53-114 Wroclaw, Poland.
Majkowski M; Laboratory of Molecular and Cellular Immunology, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Weigla 12, 53-114 Wroclaw, Poland.
Kisielow P; Laboratory of Molecular and Cellular Immunology, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Weigla 12, 53-114 Wroclaw, Poland; Laboratory of Tumor Immunology, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Weigla 1
Cebrat M; Laboratory of Molecular and Cellular Immunology, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Weigla 12, 53-114 Wroclaw, Poland. Electronic address: cebrat@iitd.pan.wroc.pl.

Dev Comp Immunol ; 81: 105-115, 2018 04.

Article em En | MEDLINE | ID: mdl-29175053

Assuntos

Imunidade Adaptativa/genética; Genes RAG-1/genética; Loci Gênicos; Regiões Promotoras Genéticas/genética; Recombinases/genética; Recombinação Genética; Animais; Sequência Conservada/genética; Elementos de DNA Transponíveis/genética; Evolução Molecular; Loci Gênicos/genética; Humanos; Imunoglobulinas/genética; Camundongos; Receptores de Antígenos de Linfócitos T/genética; Sequências Reguladoras de Ácido Nucleico; Transativadores/genética; Transcrição Gênica

Palavras-chave

Bidirectional promoter; Evolution of the adaptive immune system; NWC gene; RAG transposon

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Recombinação Genética / Regiões Promotoras Genéticas / Genes RAG-1 / Recombinases / Loci Gênicos / Imunidade Adaptativa Limite: Animals / Humans Idioma: En Revista: Dev Comp Immunol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Polônia

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