Endocannabinoid hydrolases in avian HD11 macrophages identified by chemoproteomics: inactivation by small-molecule inhibitors and pathogen-induced downregulation of their activity.

Lee, Jung Hwa; Hou, Xiang; Kummari, Evangel; Borazjani, Abdolsamad; Edelmann, Mariola J; Ross, Matthew K

Lee, Jung Hwa; Hou, Xiang; Kummari, Evangel; Borazjani, Abdolsamad; Edelmann, Mariola J; Ross, Matthew K.

Afiliação

Lee JH; Center for Environmental Health Sciences, Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS, USA.
Hou X; Center for Environmental Health Sciences, Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS, USA.
Kummari E; Institute of Food Safety, Jiangsu Academy of Agricultural Sciences, Nanjing, China.
Borazjani A; Center for Environmental Health Sciences, Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS, USA.
Edelmann MJ; Center for Environmental Health Sciences, Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS, USA.
Ross MK; Center for Environmental Health Sciences, Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS, USA.

Mol Cell Biochem ; 444(1-2): 125-141, 2018 Jul.

Article em En | MEDLINE | ID: mdl-29196970

Assuntos

Amidoidrolases/antagonistas & inibidores; Proteínas Aviárias/antagonistas & inibidores; Galinhas/metabolismo; Inibidores Enzimáticos/farmacologia; Macrófagos/enzimologia; Monoacilglicerol Lipases/antagonistas & inibidores; Infecções por Salmonella/enzimologia; Salmonella typhimurium/metabolismo; Amidoidrolases/metabolismo; Animais; Proteínas Aviárias/metabolismo; Galinhas/microbiologia; Endocanabinoides/metabolismo; Macrófagos/microbiologia; Macrófagos/patologia; Monoacilglicerol Lipases/metabolismo; Infecções por Salmonella/patologia

Palavras-chave

Activity-based protein profiling; Host defense; Macrophage; Salmonella Typhimurium; Serine hydrolases

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções por Salmonella / Salmonella typhimurium / Galinhas / Proteínas Aviárias / Inibidores Enzimáticos / Amidoidrolases / Macrófagos / Monoacilglicerol Lipases Limite: Animals Idioma: En Revista: Mol Cell Biochem Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos

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