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Epigenetic therapy activates type I interferon signaling in murine ovarian cancer to reduce immunosuppression and tumor burden.
Stone, Meredith L; Chiappinelli, Katherine B; Li, Huili; Murphy, Lauren M; Travers, Meghan E; Topper, Michael J; Mathios, Dimitrios; Lim, Michael; Shih, Ie-Ming; Wang, Tian-Li; Hung, Chien-Fu; Bhargava, Vipul; Wiehagen, Karla R; Cowley, Glenn S; Bachman, Kurtis E; Strick, Reiner; Strissel, Pamela L; Baylin, Stephen B; Zahnow, Cynthia A.
Afiliação
  • Stone ML; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21287.
  • Chiappinelli KB; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21287.
  • Li H; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21287.
  • Murphy LM; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21287.
  • Travers ME; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21287.
  • Topper MJ; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21287.
  • Mathios D; Department of Neurosurgery, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21287.
  • Lim M; Department of Neurosurgery, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21287.
  • Shih IM; Department of Gynecology and Obstetrics, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21287.
  • Wang TL; Department of Pathology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21287.
  • Hung CF; Department of Pathology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21287.
  • Bhargava V; Discovery Sciences, Janssen Research & Development, Spring House, PA 19477.
  • Wiehagen KR; Immuno-Oncology Discovery, Janssen Research & Development, Spring House, PA 19477.
  • Cowley GS; Discovery Sciences, Janssen Research & Development, Spring House, PA 19477.
  • Bachman KE; Oncology Janssen Research & Development, Spring House, PA 19477.
  • Strick R; Laboratory for Molecular Medicine, Department of Gynaecology and Obstetrics, University-Clinic Erlangen, 91054 Erlangen, Germany.
  • Strissel PL; Laboratory for Molecular Medicine, Department of Gynaecology and Obstetrics, University-Clinic Erlangen, 91054 Erlangen, Germany.
  • Baylin SB; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21287; sbaylin@jhmi.edu zahnoci@jhmi.edu.
  • Zahnow CA; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21287; sbaylin@jhmi.edu zahnoci@jhmi.edu.
Proc Natl Acad Sci U S A ; 114(51): E10981-E10990, 2017 12 19.
Article em En | MEDLINE | ID: mdl-29203668
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Transdução de Sinais / Interferon Tipo I / Epigênese Genética / Imunomodulação Limite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Transdução de Sinais / Interferon Tipo I / Epigênese Genética / Imunomodulação Limite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2017 Tipo de documento: Article