Pro-arrhythmogenic Effects of the V141M KCNQ1 Mutation in Short QT Syndrome and Its Potential Therapeutic Targets: Insights from Modeling.

Lee, Hsiang-Chun; Rudy, Yoram; Liang, Hongwu; Chen, Chih-Chieh; Luo, Ching-Hsing; Sheu, Sheng-Hsiung; Cui, Jianmin

Lee, Hsiang-Chun; Rudy, Yoram; Liang, Hongwu; Chen, Chih-Chieh; Luo, Ching-Hsing; Sheu, Sheng-Hsiung; Cui, Jianmin.

Afiliação

Lee HC; Cardiac Bioelectricity and Arrhythmia Center, Washington University in St. Louis, St. Louis, MO 63130, USA.
Rudy Y; Division of Cardiology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, 100 Tzyou 1st Rd, Kaohsiung 807, Taiwan.
Liang H; Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Chen CC; Center for Lipid Biosciences, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Luo CH; Lipid Science and Aging Research Center, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Sheu SH; Institute of Medical Science and Technology, National Sun Yat-sen University, Kaohsiung 804, Taiwan.
Cui J; Cardiac Bioelectricity and Arrhythmia Center, Washington University in St. Louis, St. Louis, MO 63130, USA.

J Med Biol Eng ; 37(5): 780-789, 2017 Oct.

Article em En | MEDLINE | ID: mdl-29213224

Palavras-chave

Anti-arrhythmic; Arrhythmia; IKs; KCNQ1; Short QT syndrome

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: J Med Biol Eng Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos

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