Prevalence of COPD in 6 Urban Clusters in Argentina: The EPOC.AR Study. / Prevalencia de enfermedad pulmonar obstructiva crónica en 6 aglomerados urbanos de Argentina: el estudio EPOC.AR.
Arch Bronconeumol (Engl Ed)
; 54(5): 260-269, 2018 May.
Article
em En, Es
| MEDLINE
| ID: mdl-29221827
ABSTRACT
INTRODUCTION:
The prevalence of chronic obstructive pulmonary disease (COPD) has not been studied in Argentina.OBJECTIVES:
To determine the prevalence and relevant clinical characteristics of COPD in a representative sample. MATERIAL ANDMETHODS:
We performed a cross-sectional study in a population of adults aged ≥ 40 years randomly selected by cluster sampling in 6 urban locations. Subjects answered a structured survey and performed pre- and post-bronchodilator spirometry (PBD). COPD was defined as FEV1/FVC ratio < 0.7 predicted value. The total prevalence was estimated for each cluster with its 95% confidence interval (CI).RESULTS:
Of 4,599 surveys and 3,999 spirometries, 3,469 were considered of adequate quality (86.8%) for our study. The prevalence of COPD was 14.5% (CI 13.4-15.7). The distribution of COPD cases according to FEV1 (GOLD 2017) was stage 1 38% (CI 34-43); stage 2 52% (CI 47-56); stage 3 10% (CI 7-13); and stage 4 1% (CI 0-2), and according to the refined ABCD (GOLD 2017) assessment A 52% (CI 47-56); B 43% (CI 39-48); C 1% (CI 0-2); D 4% (CI 2-6). The rate of underdiagnosis was 77.4% (CI 73.7-81.1%) and diagnostic error 60.7% (CI 55.1-66.3%). A significant association was found between COPD and age (OR 3.77 in individuals 50-59 years of age and 19.23 in those > 80 years), male gender (OR 1.62; CI 1.31-2), smoking (OR 1.95; CI 1.49-2.54), low socioeconomic status (OR 1.33; CI 1.02-1.73), and previous tuberculosis (OR 3.3; CI 1.43-7.62).CONCLUSIONS:
We estimate that more than 2.3 million Argentineans have COPD, with high rates of underdiagnosis and diagnostic error.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doença Pulmonar Obstrutiva Crônica
Tipo de estudo:
Clinical_trials
/
Diagnostic_studies
/
Observational_studies
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Prevalence_studies
/
Prognostic_studies
/
Qualitative_research
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Risk_factors_studies
/
Screening_studies
Limite:
Adult
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Aged
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Humans
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Middle aged
País/Região como assunto:
America do sul
/
Argentina
Idioma:
En
/
Es
Revista:
Arch Bronconeumol (Engl Ed)
Ano de publicação:
2018
Tipo de documento:
Article