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Curcumin synergizes with 5-fluorouracil by impairing AMPK/ULK1-dependent autophagy, AKT activity and enhancing apoptosis in colon cancer cells with tumor growth inhibition in xenograft mice.
Zhang, Pan; Lai, Ze-Lin; Chen, Hui-Fen; Zhang, Min; Wang, An; Jia, Tao; Sun, Wen-Qin; Zhu, Xi-Min; Chen, Xiao-Feng; Zhao, Zheng; Zhang, Jun.
Afiliação
  • Zhang P; Key Laboratory of Brain Functional Genomics (East China Normal University), Ministry of Education, School of Life Sciences, East China Normal University, Shanghai, 200062, China.
  • Lai ZL; Key Laboratory of Brain Functional Genomics (East China Normal University), Ministry of Education, School of Life Sciences, East China Normal University, Shanghai, 200062, China.
  • Chen HF; Department of Clinical Laboratory, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, 201204, China.
  • Zhang M; Department of Clinical Laboratory, Shanghai Public Health Clinical Center Affiliated to Fudan University, Shanghai, 201508, China.
  • Wang A; Department of Thoracic Surgery, Huashan Hospital, Fudan University, Shanghai, 200040, China.
  • Jia T; INSERM-UGA U1209, CNRS UMR5309, Institute for Advanced Biosciences, F-38700, La Tronche, France.
  • Sun WQ; Department of Clinical Laboratory, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, 201204, China.
  • Zhu XM; Key Laboratory of Brain Functional Genomics (East China Normal University), Ministry of Education, School of Life Sciences, East China Normal University, Shanghai, 200062, China.
  • Chen XF; Department of Thoracic Surgery, Huashan Hospital, Fudan University, Shanghai, 200040, China. dr_chenxiaofeng@126.com.
  • Zhao Z; Key Laboratory of Brain Functional Genomics (East China Normal University), Ministry of Education, School of Life Sciences, East China Normal University, Shanghai, 200062, China. zzhao@brain.ecnu.edu.cn.
  • Zhang J; Department of Clinical Laboratory, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, 201204, China. zhangjun@51mch.com.
J Exp Clin Cancer Res ; 36(1): 190, 2017 12 22.
Article em En | MEDLINE | ID: mdl-29273065
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autofagia / Protocolos de Quimioterapia Combinada Antineoplásica / Apoptose / Neoplasias do Colo / Resistencia a Medicamentos Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: J Exp Clin Cancer Res Ano de publicação: 2017 Tipo de documento: Article País de afiliação: China
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autofagia / Protocolos de Quimioterapia Combinada Antineoplásica / Apoptose / Neoplasias do Colo / Resistencia a Medicamentos Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: J Exp Clin Cancer Res Ano de publicação: 2017 Tipo de documento: Article País de afiliação: China