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Treatment of Alopecia Areata with Simvastatin/Ezetimibe.
Cervantes, Jessica; Jimenez, Joaquin J; DelCanto, Gina M; Tosti, Antonella.
Afiliação
  • Cervantes J; University of Miami Miller School of Medicine, Department of Dermatology and Cutaneous Surgery, Miami, Florida, USA.
  • Jimenez JJ; University of Miami Miller School of Medicine, Department of Dermatology and Cutaneous Surgery, Miami, Florida, USA; University of Miami Miller School of Medicine, Department of Biochemistry and Molecular Biology, Miami, Florida, USA.
  • DelCanto GM; University of Miami Miller School of Medicine, Department of Biochemistry and Molecular Biology, Miami, Florida, USA.
  • Tosti A; University of Miami Miller School of Medicine, Department of Dermatology and Cutaneous Surgery, Miami, Florida, USA. Electronic address: ATosti@med.miami.edu.
J Investig Dermatol Symp Proc ; 19(1): S25-S31, 2018 01.
Article em En | MEDLINE | ID: mdl-29273101
Alopecia areata (AA) is an autoimmune disorder characterized by T lymphocytic infiltrates around the bulbar region of hair follicles. Statins have surfaced as potential therapeutic agents for AA, partly because of their modulation of the JAK/STAT pathway. Some data indicate that statins are a possible option for acute, but not chronic, longstanding AA. Animal studies suggest that treatment with statins increases CD4+/CD25+/Foxp3+ populations in AA-affected mice.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Alopecia em Áreas / Combinação Ezetimiba e Simvastatina Limite: Animals / Humans Idioma: En Revista: J Investig Dermatol Symp Proc Assunto da revista: DERMATOLOGIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Alopecia em Áreas / Combinação Ezetimiba e Simvastatina Limite: Animals / Humans Idioma: En Revista: J Investig Dermatol Symp Proc Assunto da revista: DERMATOLOGIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos