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Identification of Morpholino-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-ones as Nonsteroidal Mineralocorticoid Antagonists.
Piotrowski, David W; Futatsugi, Kentaro; Casimiro-Garcia, Agustin; Wei, Liuqing; Sammons, Matthew F; Herr, Michael; Jiao, Wenhua; Lavergne, Sophie Y; Coffey, Steven B; Wright, Stephen W; Song, Kun; Loria, Paula M; Banker, Mary Ellen; Petersen, Donna N; Bauman, Jonathan.
Afiliação
  • Piotrowski DW; Pfizer Research and Development , Groton, Connecticut 06340, United States.
  • Futatsugi K; Pfizer Research and Development , Groton, Connecticut 06340, United States.
  • Casimiro-Garcia A; Pfizer Research and Development , Groton, Connecticut 06340, United States.
  • Wei L; Pfizer Research and Development , Groton, Connecticut 06340, United States.
  • Sammons MF; Pfizer Research and Development , Groton, Connecticut 06340, United States.
  • Herr M; Pfizer Research and Development , Groton, Connecticut 06340, United States.
  • Jiao W; Pfizer Research and Development , Groton, Connecticut 06340, United States.
  • Lavergne SY; Pfizer Research and Development , Groton, Connecticut 06340, United States.
  • Coffey SB; Pfizer Research and Development , Groton, Connecticut 06340, United States.
  • Wright SW; Pfizer Research and Development , Groton, Connecticut 06340, United States.
  • Song K; Pfizer Research and Development , Groton, Connecticut 06340, United States.
  • Loria PM; Pfizer Research and Development , Groton, Connecticut 06340, United States.
  • Banker ME; Pfizer Research and Development , Groton, Connecticut 06340, United States.
  • Petersen DN; Pfizer Research and Development , Groton, Connecticut 06340, United States.
  • Bauman J; Pfizer Research and Development , Groton, Connecticut 06340, United States.
J Med Chem ; 61(3): 1086-1097, 2018 02 08.
Article em En | MEDLINE | ID: mdl-29300474

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxazinas / Receptores de Mineralocorticoides / Antagonistas de Receptores de Mineralocorticoides / Morfolinos Tipo de estudo: Diagnostic_studies Limite: Animals / Female / Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxazinas / Receptores de Mineralocorticoides / Antagonistas de Receptores de Mineralocorticoides / Morfolinos Tipo de estudo: Diagnostic_studies Limite: Animals / Female / Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos