Your browser doesn't support javascript.
loading
Antibiotic Resistance Plasmids Cointegrated into a Megaplasmid Harboring the blaOXA-427 Carbapenemase Gene.
Desmet, Stefanie; Nepal, Suruchi; van Dijl, Jan Maarten; Van Ranst, Marc; Chlebowicz, Monika A; Rossen, John W; Van Houdt, Jeroen K J; Maes, Piet; Lagrou, Katrien; Bathoorn, Erik.
Afiliação
  • Desmet S; Department of Microbiology and Immunology, Laboratory of Clinical Bacteriology and Mycology, KU Leuven-University of Leuven, Leuven, Belgium stefanie.desmet@uzleuven.be.
  • Nepal S; University of Groningen, University Medical Center Groningen, Department of Medical Microbiology, Groningen, The Netherlands.
  • van Dijl JM; University of Groningen, University Medical Center Groningen, Department of Medical Microbiology, Groningen, The Netherlands.
  • Van Ranst M; Department of Microbiology and Immunology, Laboratory of Clinical Bacteriology and Epidemiological Virology, KU Leuven-University of Leuven, Leuven, Belgium.
  • Chlebowicz MA; University of Groningen, University Medical Center Groningen, Department of Medical Microbiology, Groningen, The Netherlands.
  • Rossen JW; University of Groningen, University Medical Center Groningen, Department of Medical Microbiology, Groningen, The Netherlands.
  • Van Houdt JKJ; Centre for Human Genetics, University Hospitals Leuven, KU Leuven, Leuven, Belgium.
  • Maes P; Department of Microbiology and Immunology, Laboratory of Clinical Bacteriology and Epidemiological Virology, KU Leuven-University of Leuven, Leuven, Belgium.
  • Lagrou K; Department of Microbiology and Immunology, Laboratory of Clinical Bacteriology and Mycology, KU Leuven-University of Leuven, Leuven, Belgium.
  • Bathoorn E; University of Groningen, University Medical Center Groningen, Department of Medical Microbiology, Groningen, The Netherlands.
Antimicrob Agents Chemother ; 62(3)2018 03.
Article em En | MEDLINE | ID: mdl-29311088
ABSTRACT
OXA-427 is a new class D carbapenemase encountered in different species of Enterobacteriaceae in a Belgian hospital. To study the dispersal of this gene, we performed a comparative analysis of two plasmids containing the blaOXA-427 gene, isolated from a Klebsiella pneumoniae strain and an Enterobacter cloacae complex strain. The two IncA/C2 plasmids containing blaOXA-427 share the same backbone; in the K. pneumoniae strain, however, this plasmid is cointegrated into an IncFIb plasmid, forming a 321-kb megaplasmid with multiple multiresistance regions.
Assuntos
Palavras-chave
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Plasmídeos / Proteínas de Bactérias / Beta-Lactamases Idioma: En Revista: Antimicrob Agents Chemother Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Bélgica
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Plasmídeos / Proteínas de Bactérias / Beta-Lactamases Idioma: En Revista: Antimicrob Agents Chemother Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Bélgica