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Germline BRCA mutation and outcome in young-onset breast cancer (POSH): a prospective cohort study.
Copson, Ellen R; Maishman, Tom C; Tapper, Will J; Cutress, Ramsey I; Greville-Heygate, Stephanie; Altman, Douglas G; Eccles, Bryony; Gerty, Sue; Durcan, Lorraine T; Jones, Louise; Evans, D Gareth; Thompson, Alastair M; Pharoah, Paul; Easton, Douglas F; Dunning, Alison M; Hanby, Andrew; Lakhani, Sunil; Eeles, Ros; Gilbert, Fiona J; Hamed, Hisham; Hodgson, Shirley; Simmonds, Peter; Stanton, Louise; Eccles, Diana M.
Afiliação
  • Copson ER; Cancer Sciences Academic Unit, Faculty of Medicine, University of Southampton, Southampton, UK.
  • Maishman TC; Southampton Clinical Trials Unit, University of Southampton, Southampton, UK.
  • Tapper WJ; Genetic Epidemiology and Genomic Informatics Group, Human Genetics, Faculty of Medicine, University of Southampton, Southampton, UK.
  • Cutress RI; Cancer Sciences Academic Unit, Faculty of Medicine, University of Southampton, Southampton, UK.
  • Greville-Heygate S; Cancer Sciences Academic Unit, Faculty of Medicine, University of Southampton, Southampton, UK; University Hospital Southampton NHS Foundation Trust, Southampton, UK.
  • Altman DG; Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology & Musculoskeletal Sciences, University of Oxford, Oxford, UK.
  • Eccles B; Cancer Sciences Academic Unit, Faculty of Medicine, University of Southampton, Southampton, UK.
  • Gerty S; Southampton Clinical Trials Unit, University of Southampton, Southampton, UK.
  • Durcan LT; Southampton Clinical Trials Unit, University of Southampton, Southampton, UK.
  • Jones L; Tumour Biology Department, Institute of Cancer, Barts and The London School of Medicine & Dentistry, London, UK.
  • Evans DG; Centre for Genomic Medicine, Division of Evolution and Genomic Sciences, University of Manchester MAHSC, St Mary's Hospital, Manchester, UK.
  • Thompson AM; University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Pharoah P; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
  • Easton DF; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
  • Dunning AM; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
  • Hanby A; Department of Pathology, University of Leeds, Faculty of Medicine, Leeds, UK.
  • Lakhani S; Discipline of Molecular & Cellular Pathology, Faculty of Medicine, University of Queensland, The Royal Brisbane & Women's Hospital, Brisbane, QLD, Australia.
  • Eeles R; Institute of Cancer Research, London, UK.
  • Gilbert FJ; Department of Radiology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.
  • Hamed H; Guy's & St Thomas' Hospital, London, UK.
  • Hodgson S; St George's Hospital, University of London, London, UK.
  • Simmonds P; University Hospital Southampton NHS Foundation Trust, Southampton, UK.
  • Stanton L; Southampton Clinical Trials Unit, University of Southampton, Southampton, UK.
  • Eccles DM; Cancer Sciences Academic Unit, Faculty of Medicine, University of Southampton, Southampton, UK; University Hospital Southampton NHS Foundation Trust, Southampton, UK. Electronic address: d.m.eccles@soton.ac.uk.
Lancet Oncol ; 19(2): 169-180, 2018 02.
Article em En | MEDLINE | ID: mdl-29337092

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Mutação em Linhagem Germinativa / Genes BRCA1 / Predisposição Genética para Doença / Genes BRCA2 Tipo de estudo: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Female / Humans País/Região como assunto: Europa Idioma: En Revista: Lancet Oncol Assunto da revista: NEOPLASIAS Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Mutação em Linhagem Germinativa / Genes BRCA1 / Predisposição Genética para Doença / Genes BRCA2 Tipo de estudo: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Female / Humans País/Região como assunto: Europa Idioma: En Revista: Lancet Oncol Assunto da revista: NEOPLASIAS Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Reino Unido