Aortic dysfunction in metabolic syndrome mediated by perivascular adipose tissue TNF&#945;- and NOX2-dependent pathway.

DeVallance, Evan; Branyan, Kayla W; Lemaster, Kent; Olfert, I Mark; Smith, David M; Pistilli, Emidio E; Frisbee, Jefferson C; Chantler, Paul D

Aortic dysfunction in metabolic syndrome mediated by perivascular adipose tissue TNFα- and NOX2-dependent pathway.

DeVallance, Evan; Branyan, Kayla W; Lemaster, Kent; Olfert, I Mark; Smith, David M; Pistilli, Emidio E; Frisbee, Jefferson C; Chantler, Paul D.

Afiliação

DeVallance E; Division of Exercise Physiology, West Virginia University School of Medicine, Morgantown, WV, USA.
Branyan KW; Division of Exercise Physiology, West Virginia University School of Medicine, Morgantown, WV, USA.
Lemaster K; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON, Canada.
Olfert IM; Division of Exercise Physiology, West Virginia University School of Medicine, Morgantown, WV, USA.
Smith DM; Department of Biochemistry, West Virginia University School of Medicine, Morgantown, WV, USA.
Pistilli EE; Division of Exercise Physiology, West Virginia University School of Medicine, Morgantown, WV, USA.
Frisbee JC; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON, Canada.
Chantler PD; Department of Medical Biophysics, Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON, Canada.

Exp Physiol ; 103(4): 590-603, 2018 04 01.

Article em En | MEDLINE | ID: mdl-29349831

Assuntos

Tecido Adiposo/metabolismo; Tecido Adiposo/fisiopatologia; Aorta/metabolismo; Aorta/fisiopatologia; Síndrome Metabólica/fisiopatologia; NADPH Oxidase 2/metabolismo; Fator de Necrose Tumoral alfa/metabolismo; Animais; Endotélio Vascular/metabolismo; Endotélio Vascular/fisiopatologia; Masculino; Metaloproteinase 9 da Matriz/metabolismo; Síndrome Metabólica/metabolismo; Óxido Nítrico/metabolismo; Complexo de Endopeptidases do Proteassoma/metabolismo; Ratos; Ratos Zucker; Espécies Reativas de Oxigênio/metabolismo; Transdução de Sinais/fisiologia

Palavras-chave

metabolic syndrome; perivascular adipose tissue; tumour necrosis factor-α

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Aorta / Tecido Adiposo / Fator de Necrose Tumoral alfa / Síndrome Metabólica / NADPH Oxidase 2 Limite: Animals Idioma: En Revista: Exp Physiol Assunto da revista: FISIOLOGIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos

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