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Inhibition of lysyl oxidase-like 1 (LOXL1) expression arrests liver fibrosis progression in cirrhosis by reducing elastin crosslinking.
Zhao, Wenshan; Yang, Aiting; Chen, Wei; Wang, Ping; Liu, Tianhui; Cong, Min; Xu, Anjian; Yan, Xuzhen; Jia, Jidong; You, Hong.
Afiliação
  • Zhao W; Liver Research Center, Beijing Key Laboratory of Translational Medicine in Liver Cirrhosis, Beijing Friendship Hospital, Capital Medical University, Beijing, China; National Clinical Research Center of Digestive Diseases, Beijing, China.
  • Yang A; Experimental and Translational Research Center, Beijing Friendship Hospital, Capital Medical University, Beijing, China; National Clinical Research Center of Digestive Diseases, Beijing, China.
  • Chen W; Experimental and Translational Research Center, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
  • Wang P; Liver Research Center, Beijing Key Laboratory of Translational Medicine in Liver Cirrhosis, Beijing Friendship Hospital, Capital Medical University, Beijing, China; National Clinical Research Center of Digestive Diseases, Beijing, China.
  • Liu T; Liver Research Center, Beijing Key Laboratory of Translational Medicine in Liver Cirrhosis, Beijing Friendship Hospital, Capital Medical University, Beijing, China; National Clinical Research Center of Digestive Diseases, Beijing, China.
  • Cong M; Liver Research Center, Beijing Key Laboratory of Translational Medicine in Liver Cirrhosis, Beijing Friendship Hospital, Capital Medical University, Beijing, China; National Clinical Research Center of Digestive Diseases, Beijing, China.
  • Xu A; Experimental and Translational Research Center, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
  • Yan X; Liver Research Center, Beijing Key Laboratory of Translational Medicine in Liver Cirrhosis, Beijing Friendship Hospital, Capital Medical University, Beijing, China; National Clinical Research Center of Digestive Diseases, Beijing, China.
  • Jia J; Liver Research Center, Beijing Key Laboratory of Translational Medicine in Liver Cirrhosis, Beijing Friendship Hospital, Capital Medical University, Beijing, China; National Clinical Research Center of Digestive Diseases, Beijing, China.
  • You H; Liver Research Center, Beijing Key Laboratory of Translational Medicine in Liver Cirrhosis, Beijing Friendship Hospital, Capital Medical University, Beijing, China; National Clinical Research Center of Digestive Diseases, Beijing, China. Electronic address: youhongliver@ccmu.edu.cn.
Biochim Biophys Acta Mol Basis Dis ; 1864(4 Pt A): 1129-1137, 2018 Apr.
Article em En | MEDLINE | ID: mdl-29366776
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Regulação Enzimológica da Expressão Gênica / Elastina / Aminoácido Oxirredutases / Cirrose Hepática Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Biochim Biophys Acta Mol Basis Dis Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Regulação Enzimológica da Expressão Gênica / Elastina / Aminoácido Oxirredutases / Cirrose Hepática Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Biochim Biophys Acta Mol Basis Dis Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China