Generation of ApoE deficient dogs via combination of embryo injection of CRISPR/Cas9 with somatic cell nuclear transfer.

Feng, Chong; Wang, Xiaomin; Shi, Hui; Yan, Quanmei; Zheng, Min; Li, Jing; Zhang, Quanjun; Qin, Yumin; Zhong, Yougang; Mi, Jidong; Lai, Liangxue

Feng, Chong; Wang, Xiaomin; Shi, Hui; Yan, Quanmei; Zheng, Min; Li, Jing; Zhang, Quanjun; Qin, Yumin; Zhong, Yougang; Mi, Jidong; Lai, Liangxue.

Afiliação

Feng C; Beijing SINOGENE Biotechnology Co., Ltd, Beijing 102200, China.
Wang X; Key Laboratory of Regenerative Biology of the Chinese Academy of Sciences and Guangdong Provincial Key Laboratory of Stem Cells and Regenerative Medicine, Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China; University of Chinese Academy of Sciences, Beijing 10
Shi H; Key Laboratory of Regenerative Biology of the Chinese Academy of Sciences and Guangdong Provincial Key Laboratory of Stem Cells and Regenerative Medicine, Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China; University of Chinese Academy of Sciences, Beijing 10
Yan Q; Key Laboratory of Regenerative Biology of the Chinese Academy of Sciences and Guangdong Provincial Key Laboratory of Stem Cells and Regenerative Medicine, Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China.
Zheng M; Beijing SINOGENE Biotechnology Co., Ltd, Beijing 102200, China.
Li J; Beijing SINOGENE Biotechnology Co., Ltd, Beijing 102200, China.
Zhang Q; Key Laboratory of Regenerative Biology of the Chinese Academy of Sciences and Guangdong Provincial Key Laboratory of Stem Cells and Regenerative Medicine, Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China.
Qin Y; College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.
Zhong Y; College of Veterinary Medicine, China Agricultural University, Beijing 100193, China. Electronic address: 18911223116@126.com.
Mi J; Beijing SINOGENE Biotechnology Co., Ltd, Beijing 102200, China. Electronic address: jidong-m@sinogene.com.cn.
Lai L; Key Laboratory of Regenerative Biology of the Chinese Academy of Sciences and Guangdong Provincial Key Laboratory of Stem Cells and Regenerative Medicine, Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China; Jilin Provincial Key Laboratory of Animal Embryo Engi

J Genet Genomics ; 45(1): 47-50, 2018 01 20.

Article em En | MEDLINE | ID: mdl-29396142

Assuntos

Apolipoproteínas E/genética; Sistemas CRISPR-Cas/genética; Desenvolvimento Embrionário/genética; Técnicas de Transferência Nuclear; Animais; Cães; Embrião de Mamíferos; Fibroblastos/citologia; Edição de Genes; Técnicas de Inativação de Genes; Zigoto/citologia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Apolipoproteínas E / Desenvolvimento Embrionário / Técnicas de Transferência Nuclear / Sistemas CRISPR-Cas Limite: Animals Idioma: En Revista: J Genet Genomics Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China

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