Attenuation of reactive gliosis in stroke-injured mouse brain does not affect neurogenesis from grafted human iPSC-derived neural progenitors.

Laterza, Cecilia; Uoshima, Naomi; Tornero, Daniel; Wilhelmsson, Ulrika; Stokowska, Anna; Ge, Ruimin; Pekny, Milos; Lindvall, Olle; Kokaia, Zaal

Laterza, Cecilia; Uoshima, Naomi; Tornero, Daniel; Wilhelmsson, Ulrika; Stokowska, Anna; Ge, Ruimin; Pekny, Milos; Lindvall, Olle; Kokaia, Zaal.

Afiliação

Laterza C; Department of Clinical Sciences, Laboratory of Stem Cells & Restorative Neurology, Lund Stem Cell Center, University Hospital, Lund, Sweden.
Uoshima N; Department of Clinical Sciences, Laboratory of Stem Cells & Restorative Neurology, Lund Stem Cell Center, University Hospital, Lund, Sweden.
Tornero D; Department of Anesthesiology, Tokyo Medical University, Nishishinjuku, Shinjuku-ku, Tokyo, Japan.
Wilhelmsson U; Department of Clinical Sciences, Laboratory of Stem Cells & Restorative Neurology, Lund Stem Cell Center, University Hospital, Lund, Sweden.
Stokowska A; Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Laboratory of Astrocyte Biology and CNS Regeneration, Center for Brain Repair, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
Ge R; Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Laboratory of Regenerative Neuroimmunology, Center for Brain Repair, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
Pekny M; Department of Clinical Sciences, Laboratory of Stem Cells & Restorative Neurology, Lund Stem Cell Center, University Hospital, Lund, Sweden.
Lindvall O; Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Laboratory of Astrocyte Biology and CNS Regeneration, Center for Brain Repair, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
Kokaia Z; Department of Clinical Sciences, Laboratory of Stem Cells & Restorative Neurology, Lund Stem Cell Center, University Hospital, Lund, Sweden.

PLoS One ; 13(2): e0192118, 2018.

Article em En | MEDLINE | ID: mdl-29401502

Assuntos

Gliose/prevenção & controle; Células-Tronco Pluripotentes Induzidas/transplante; Células-Tronco Neurais/transplante; Neurogênese; Acidente Vascular Cerebral/patologia; Animais; Proteína Glial Fibrilar Ácida/genética; Humanos; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Mutação

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Acidente Vascular Cerebral / Neurogênese / Células-Tronco Pluripotentes Induzidas / Células-Tronco Neurais / Gliose Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Suécia

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