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Multiple Synchronous Sporadic Gastrointestinal Stromal Tumors in the Stomach and Jejunum.
Tokunaga, Mami; Nanjo, Sohachi; Yoshita, Hiroki; Fujinami, Haruka; Watanabe, Tohru; Ishii, Yoko; Kobayashi, Saito; Akashi, Momoko; Takagi, Hiroaki; Mihara, Hiroshi; Kajiura, Shinya; Ando, Takayuki; Hashimoto, Isaya; Hojo, Shozo; Okumura, Tomoyuki; Sugiyama, Toshiro.
Afiliação
  • Tokunaga M; Department of Gastroenterology and Hematology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Japan.
  • Nanjo S; Department of Gastroenterology and Hematology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Japan.
  • Yoshita H; Department of Gastroenterology and Hematology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Japan.
  • Fujinami H; Department of Gastroenterology and Hematology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Japan.
  • Watanabe T; Department of Surgery and Science, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Japan.
  • Ishii Y; Department of Pathology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Japan.
  • Kobayashi S; Department of Gastroenterology and Hematology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Japan.
  • Akashi M; Department of Gastroenterology and Hematology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Japan.
  • Takagi H; Department of Gastroenterology and Hematology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Japan.
  • Mihara H; Department of Gastroenterology and Hematology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Japan.
  • Kajiura S; Department of Gastroenterology and Hematology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Japan.
  • Ando T; Department of Gastroenterology and Hematology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Japan.
  • Hashimoto I; Department of Surgery and Science, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Japan.
  • Hojo S; Department of Surgery and Science, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Japan.
  • Okumura T; Department of Surgery and Science, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Japan.
  • Sugiyama T; Department of Gastroenterology and Hematology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Japan.
Intern Med ; 57(12): 1719-1723, 2018 Jun 15.
Article em En | MEDLINE | ID: mdl-29434135
ABSTRACT
A 77-year-old patient was admitted to our hospital for the further examination of melena. A computed tomography scan detected two submucosal tumors (SMTs) in the stomach and jejunum. Double-balloon endoscopy revealed the presence of a delle on the jejunal SMT, suggesting that the SMT was the origin of the gastrointestinal bleeding. Both tumors were surgically resected and subsequently diagnosed via histology as gastrointestinal stromal tumors (GISTs). Furthermore, the two GISTs had different mutations in the c-kit gene, suggesting that they were derived from different clonal origins. This report depicts an extremely rare case of multiple synchronous sporadic GISTs in the stomach and jejunum.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas / Tumores do Estroma Gastrointestinal / Neoplasias do Jejuno Tipo de estudo: Diagnostic_studies Limite: Aged / Humans / Male Idioma: En Revista: Intern Med Assunto da revista: MEDICINA INTERNA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Japão

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas / Tumores do Estroma Gastrointestinal / Neoplasias do Jejuno Tipo de estudo: Diagnostic_studies Limite: Aged / Humans / Male Idioma: En Revista: Intern Med Assunto da revista: MEDICINA INTERNA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Japão