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Oncogenic activation of JAK3-STAT signaling confers clinical sensitivity to PRN371, a novel selective and potent JAK3 inhibitor, in natural killer/T-cell lymphoma.
Nairismägi, M -L; Gerritsen, M E; Li, Z M; Wijaya, G C; Chia, B K H; Laurensia, Y; Lim, J Q; Yeoh, K W; Yao, X S; Pang, W L; Bisconte, A; Hill, R J; Bradshaw, J M; Huang, D; Song, T L L; Ng, C C Y; Rajasegaran, V; Tang, T; Tang, Q Q; Xia, X J; Kang, T B; Teh, B T; Lim, S T; Ong, C K; Tan, J.
Afiliação
  • Nairismägi M-; Lymphoma Genomic Translational Research Laboratory, Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore.
  • Gerritsen ME; Principia Biopharma, South San Francisco, CA, USA.
  • Li ZM; Laboratory of Cancer Epigenome, Division of Medical Sciences, National Cancer Centre Singapore, Singapore, Singapore.
  • Wijaya GC; Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore, Singapore.
  • Chia BKH; Laboratory of Cancer Epigenome, Division of Medical Sciences, National Cancer Centre Singapore, Singapore, Singapore.
  • Laurensia Y; Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore, Singapore.
  • Lim JQ; Lymphoma Genomic Translational Research Laboratory, Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore.
  • Yeoh KW; Lymphoma Genomic Translational Research Laboratory, Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore.
  • Yao XS; Lymphoma Genomic Translational Research Laboratory, Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore.
  • Pang WL; Department of Radiation Oncology, National Cancer Centre Singapore, Singapore, Singapore.
  • Bisconte A; Laboratory of Cancer Epigenome, Division of Medical Sciences, National Cancer Centre Singapore, Singapore, Singapore.
  • Hill RJ; Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore, Singapore.
  • Bradshaw JM; Lymphoma Genomic Translational Research Laboratory, Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore.
  • Huang D; Principia Biopharma, South San Francisco, CA, USA.
  • Song TLL; Principia Biopharma, South San Francisco, CA, USA.
  • Ng CCY; Principia Biopharma, South San Francisco, CA, USA.
  • Rajasegaran V; Lymphoma Genomic Translational Research Laboratory, Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore.
  • Tang T; Lymphoma Genomic Translational Research Laboratory, Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore.
  • Tang QQ; Laboratory of Cancer Epigenome, Division of Medical Sciences, National Cancer Centre Singapore, Singapore, Singapore.
  • Xia XJ; Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore, Singapore.
  • Kang TB; Laboratory of Cancer Epigenome, Division of Medical Sciences, National Cancer Centre Singapore, Singapore, Singapore.
  • Teh BT; Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore, Singapore.
  • Lim ST; Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore.
  • Ong CK; Laboratory of Cancer Epigenome, Division of Medical Sciences, National Cancer Centre Singapore, Singapore, Singapore.
  • Tan J; Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore, Singapore.
Leukemia ; 32(5): 1147-1156, 2018 05.
Article em En | MEDLINE | ID: mdl-29434279
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piridonas / Pirimidinas / Transdução de Sinais / Linfoma de Células T / Fatores de Transcrição STAT / Janus Quinase 3 Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Leukemia Assunto da revista: HEMATOLOGIA / NEOPLASIAS Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Singapura
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piridonas / Pirimidinas / Transdução de Sinais / Linfoma de Células T / Fatores de Transcrição STAT / Janus Quinase 3 Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Leukemia Assunto da revista: HEMATOLOGIA / NEOPLASIAS Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Singapura