Down's syndrome and the gastrointestinal tract.
J Clin Gastroenterol
; 8(2): 111-4, 1986 Apr.
Article
em En
| MEDLINE
| ID: mdl-2943789
ABSTRACT
Gastrointestinal (GI) abnormalities are frequent in patients with Down's syndrome. In a 12-year retrospective review, we identified 187 patients with Down's syndrome admitted to the Columbia-Presbyterian Medical Center. Twenty-seven had major GI disorders, the most common being duodenal stenosis (DS, nine), gastroesophageal reflux (GER, five), imperforate anus (five), and Hirschsprung's disease (four). The mortality for the whole group was 11% (20 patients). The mortality in the small group of patients with duodenal stenosis was particularly high (five out of nine, or 56%). Associated congenital heart disease, especially endocardial cushion defects, and the frequent occurrence of pneumonia contributed to this high mortality rate.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Síndrome de Down
/
Anormalidades do Sistema Digestório
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Female
/
Humans
/
Infant
/
Male
Idioma:
En
Revista:
J Clin Gastroenterol
Ano de publicação:
1986
Tipo de documento:
Article