"Cooperative collapse" of the denatured state revealed through Clausius-Clapeyron analysis of protein denaturation phase diagrams.

Tischer, Alexander; Machha, Venkata R; Rösgen, Jörg; Auton, Matthew

Tischer, Alexander; Machha, Venkata R; Rösgen, Jörg; Auton, Matthew.

Afiliação

Tischer A; Division of Hematology, Departments of Internal Medicine and Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota.
Machha VR; Division of Hematology, Departments of Internal Medicine and Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota.
Rösgen J; Department Biochemistry and Molecular Biology, Penn State University College of Medicine, Hershey, Pennsylvania, 17033.
Auton M; Division of Hematology, Departments of Internal Medicine and Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota.

Biopolymers ; 109(8): e23106, 2018 Aug.

Article em En | MEDLINE | ID: mdl-29457634

Assuntos

Modelos Químicos; Desnaturação Proteica; Proteínas/química; Ureia/química

Palavras-chave

Clausius-Clapeyron equation; denatured state collapse; disulfide bond; urea-temperature phase diagram; von Willebrand factor

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Desnaturação Proteica / Ureia / Proteínas / Modelos Químicos Tipo de estudo: Prognostic_studies Idioma: En Revista: Biopolymers Ano de publicação: 2018 Tipo de documento: Article

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