Cryoprecipitate transfusions in the neonatal intensive care unit: a performance improvement study to decrease donor exposure.
Transfusion
; 58(5): 1206-1209, 2018 05.
Article
em En
| MEDLINE
| ID: mdl-29479718
ABSTRACT
BACKGROUND:
The objective of this study was to determine if a change in cryoprecipitate transfusion policy impacts donor exposure and fibrinogen level in a neonatal intensive care unit (NICU) population. STUDY DESIGN ANDMETHODS:
The cryoprecipitate policy was changed from transfusing 10ml/kg to a maximum of 1 unit per transfusion in January 2013. Data were obtained via retrospective chart review of all infants receiving cryoprecipitate transfusions from January 2008 to February 2015 in the NICU at Christiana Hospital.RESULTS:
A total of 103 neonates received a total of 144 cryoprecipitate transfusions. Before the policy change, term babies were more likely to be exposed to more than one donor compared to preterm babies (75% vs. 6%, p < 0.01). After the policy change, no babies were exposed to greater than one donor per transfusion and there were similar increases in posttransfusion fibrinogen level as before the policy change.CONCLUSION:
Limiting cryoprecipitate transfusions to 1 unit per transfusion decreased donor exposure in infants without negatively impacting posttransfusion fibrinogen levels. This is especially evident in term neonates.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doadores de Tecidos
/
Transfusão de Sangue
/
Unidades de Terapia Intensiva Neonatal
Tipo de estudo:
Observational_studies
/
Prognostic_studies
Limite:
Humans
/
Infant
/
Newborn
Idioma:
En
Revista:
Transfusion
Ano de publicação:
2018
Tipo de documento:
Article