Kinetic analysis of oxime-assisted reactivation of human, Guinea pig, and rat acetylcholinesterase inhibited by the organophosphorus pesticide metabolite phorate oxon (PHO).

Moyer, Robert A; McGarry, Kevin G; Babin, Michael C; Platoff, Gennady E; Jett, David A; Yeung, David T

Moyer, Robert A; McGarry, Kevin G; Babin, Michael C; Platoff, Gennady E; Jett, David A; Yeung, David T.

Afiliação

Moyer RA; Battelle, Columbus, OH, United States. Electronic address: moyerr@battelle.org.
McGarry KG; Battelle, Columbus, OH, United States.
Babin MC; Battelle, Columbus, OH, United States.
Platoff GE; National Institutes of Health/National Institute of Allergy and Infectious Diseases, Rockville, MD, United States.
Jett DA; National Institutes of Health/National Institute of Neurological Disorders and Stroke, Rockville, MD, United States.
Yeung DT; National Institutes of Health/National Institute of Allergy and Infectious Diseases, Rockville, MD, United States.

Pestic Biochem Physiol ; 145: 93-99, 2018 Feb.

Article em En | MEDLINE | ID: mdl-29482737

Assuntos

Acetilcolinesterase/metabolismo; Inibidores da Colinesterase/metabolismo; Reativadores da Colinesterase/farmacologia; Cloreto de Obidoxima/farmacologia; Oximas/metabolismo; Praguicidas/toxicidade; Forato/toxicidade; Animais; Antídotos/farmacologia; Inibidores da Colinesterase/toxicidade; Reativadores da Colinesterase/metabolismo; Cobaias; Humanos; Cinética; Cloreto de Obidoxima/metabolismo; Oximas/farmacologia; Ratos

Palavras-chave

Acetylcholinesterase; Kinetics; Oxime; Phorate

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oximas / Praguicidas / Forato / Acetilcolinesterase / Inibidores da Colinesterase / Reativadores da Colinesterase / Cloreto de Obidoxima Limite: Animals / Humans Idioma: En Revista: Pestic Biochem Physiol Ano de publicação: 2018 Tipo de documento: Article

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