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Binding Mode Characterization and Early in Vivo Evaluation of Fragment-Like Thiols as Inhibitors of the Virulence Factor LasB from Pseudomonas aeruginosa.
Kany, Andreas M; Sikandar, Asfandyar; Haupenthal, Jörg; Yahiaoui, Samir; Maurer, Christine K; Proschak, Ewgenij; Köhnke, Jesko; Hartmann, Rolf W.
Afiliação
  • Kany AM; Department of Drug Design and Optimization , Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) , Campus E8.1 , 66123 , Saarbrücken , Germany.
  • Sikandar A; Workgroup Structural Biology of Biosynthetic Enzymes , Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) , Campus E8.1 , 66123 , Saarbrücken , Germany.
  • Haupenthal J; Department of Drug Design and Optimization , Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) , Campus E8.1 , 66123 , Saarbrücken , Germany.
  • Yahiaoui S; Department of Drug Design and Optimization , Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) , Campus E8.1 , 66123 , Saarbrücken , Germany.
  • Maurer CK; Department of Drug Design and Optimization , Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) , Campus E8.1 , 66123 , Saarbrücken , Germany.
  • Proschak E; Institute of Pharmaceutical Chemistry , Goethe University Frankfurt , Max-von-Laue-Straße 9 , 60438 , Frankfurt , Germany.
  • Köhnke J; Workgroup Structural Biology of Biosynthetic Enzymes , Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) , Campus E8.1 , 66123 , Saarbrücken , Germany.
  • Hartmann RW; Department of Drug Design and Optimization , Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) , Campus E8.1 , 66123 , Saarbrücken , Germany.
ACS Infect Dis ; 4(6): 988-997, 2018 06 08.
Article em En | MEDLINE | ID: mdl-29485268
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pseudomonas aeruginosa / Compostos de Sulfidrila / Proteínas de Bactérias / Metaloendopeptidases / Antibacterianos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: ACS Infect Dis Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pseudomonas aeruginosa / Compostos de Sulfidrila / Proteínas de Bactérias / Metaloendopeptidases / Antibacterianos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: ACS Infect Dis Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha