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Pharmacological disruption of the MID1/α4 interaction reduces mutant Huntingtin levels in primary neuronal cultures.
Monteiro, Olivia; Chen, Changwei; Bingham, Ryan; Argyrou, Argyrides; Buxton, Rachel; Pancevac Jönsson, Christina; Jones, Emma; Bridges, Angela; Gatfield, Kelly; Krauß, Sybille; Lambert, Jeremy; Langston, Rosamund; Schweiger, Susann; Uings, Iain.
Afiliação
  • Monteiro O; Division of Neuroscience, University of Dundee, UK.
  • Chen C; Division of Neuroscience, University of Dundee, UK.
  • Bingham R; Platform Technology and Sciences,GlaxoSmithKline, UK.
  • Argyrou A; Platform Technology and Sciences,GlaxoSmithKline, UK.
  • Buxton R; Platform Technology and Sciences,GlaxoSmithKline, UK.
  • Pancevac Jönsson C; Platform Technology and Sciences,GlaxoSmithKline, UK.
  • Jones E; Platform Technology and Sciences,GlaxoSmithKline, UK.
  • Bridges A; Platform Technology and Sciences,GlaxoSmithKline, UK.
  • Gatfield K; Platform Technology and Sciences,GlaxoSmithKline, UK.
  • Krauß S; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
  • Lambert J; Division of Neuroscience, University of Dundee, UK.
  • Langston R; Division of Neuroscience, University of Dundee, UK.
  • Schweiger S; Department of Human Genetics, University of Mainz, Germany.
  • Uings I; Discovery Partnerships with Academia,GlaxoSmithKline, UK. Electronic address: iain.j.uings@gsk.com.
Neurosci Lett ; 673: 44-50, 2018 04 23.
Article em En | MEDLINE | ID: mdl-29499308

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas / Proteína Huntingtina / Neurônios Limite: Animals / Humans Idioma: En Revista: Neurosci Lett Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas / Proteína Huntingtina / Neurônios Limite: Animals / Humans Idioma: En Revista: Neurosci Lett Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Reino Unido