Icariin attenuates titanium particle-induced inhibition of osteogenic differentiation and matrix mineralization via miR-21-5p.

Lian, Feng; Zhao, Chengbin; Qu, Jing; Lian, Yongyun; Cui, Yong; Shan, Liang; Yan, Jinglong

Lian, Feng; Zhao, Chengbin; Qu, Jing; Lian, Yongyun; Cui, Yong; Shan, Liang; Yan, Jinglong.

Afiliação

Lian F; Department of Orthopaedic Surgery, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, 150001, People's Republic of China.
Zhao C; Department of Orthopaedic Surgery, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, 150001, People's Republic of China.
Qu J; Department of Orthopaedic Surgery, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, 150001, People's Republic of China.
Lian Y; Department of Orthopaedic Surgery, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, 150001, People's Republic of China.
Cui Y; Department of Orthopaedic Surgery, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, 150001, People's Republic of China.
Shan L; Department of Outpatient, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, 150001, People's Republic of China.
Yan J; Department of Orthopaedic Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, 150001, People's Republic of China.

Cell Biol Int ; 42(8): 931-939, 2018 Aug.

Article em En | MEDLINE | ID: mdl-29500883

Assuntos

Diferenciação Celular/efeitos dos fármacos; Flavonoides/farmacologia; MicroRNAs/metabolismo; Osteogênese/efeitos dos fármacos; Titânio/farmacologia; Fosfatase Alcalina/metabolismo; Ligas/química; Animais; Antagomirs/metabolismo; Proteína Morfogenética Óssea 2/metabolismo; Linhagem Celular; Subunidade alfa 1 de Fator de Ligação ao Core/metabolismo; Camundongos; MicroRNAs/antagonistas & inibidores; MicroRNAs/genética; Osteocalcina/metabolismo; Titânio/química; Regulação para Cima/efeitos dos fármacos

Palavras-chave

Icariin; matrix mineralization; miR-21-5p; osteoblast differentiation; titanium particles

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteogênese / Titânio / Flavonoides / Diferenciação Celular / MicroRNAs Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Cell Biol Int Ano de publicação: 2018 Tipo de documento: Article

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