Transgenic Expression of A Venous Malformation Related Mutation, <i>TIE2-R849W</i>, Significantly Induces Multiple Malformations of Zebrafish.

Du, Zhong; Ma, Hai-Long; Zhang, Zhi-Yuan; Zheng, Jia-Wei; Wang, Yan-An

Transgenic Expression of A Venous Malformation Related Mutation, TIE2-R849W, Significantly Induces Multiple Malformations of Zebrafish.

Du, Zhong; Ma, Hai-Long; Zhang, Zhi-Yuan; Zheng, Jia-Wei; Wang, Yan-An.

Afiliação

Du Z; Department of Oral and Maxillofacial-Head and Neck Oncology, Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology, Shanghai, 200011, PR China.
Ma HL; Department of Oral and Maxillofacial-Head and Neck Oncology, Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology, Shanghai, 200011, PR China.
Zhang ZY; Department of Oral and Maxillofacial-Head and Neck Oncology, Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology, Shanghai, 200011, PR China.
Zheng JW; Department of Oral and Maxillofacial-Head and Neck Oncology, Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology, Shanghai, 200011, PR China.
Wang YA; Department of Oral and Maxillofacial-Head and Neck Oncology, Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology, Shanghai, 200011, PR China.

Int J Med Sci ; 15(4): 385-394, 2018.

Article em En | MEDLINE | ID: mdl-29511374

Assuntos

Malformações Vasculares/genética; Veias/patologia; Proteínas de Peixe-Zebra/genética; Animais; Animais Geneticamente Modificados; Modelos Animais de Doenças; Regulação da Expressão Gênica/genética; Humanos; Mutação; Fosforilação; Receptor TIE-2/genética; Malformações Vasculares/patologia; Veias/metabolismo; Peixe-Zebra/genética

Palavras-chave

Developmental malformation; Egfl7; TIE2-R849W; Venous malformation; Wnt; Zebrafish

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Veias / Proteínas de Peixe-Zebra / Malformações Vasculares Limite: Animals / Humans Idioma: En Revista: Int J Med Sci Assunto da revista: MEDICINA Ano de publicação: 2018 Tipo de documento: Article

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