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Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of CSF1R and NOTCH3.
Sassi, Celeste; Nalls, Michael A; Ridge, Perry G; Gibbs, Jesse R; Lupton, Michelle K; Troakes, Claire; Lunnon, Katie; Al-Sarraj, Safa; Brown, Kristelle S; Medway, Christopher; Lord, Jenny; Turton, James; Bras, Jose; Blumenau, Sonja; Thielke, Mareike; Josties, Christa; Freyer, Dorette; Dietrich, Annette; Hammer, Monia; Baier, Michael; Dirnagl, Ulrich; Morgan, Kevin; Powell, John F; Kauwe, John S; Cruchaga, Carlos; Goate, Alison M; Singleton, Andrew B; Guerreiro, Rita; Hodges, Angela; Hardy, John.
Afiliação
  • Sassi C; Reta Lila, Weston Research Laboratories, Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA; Department of Experimental Neurology, Center for Stroke Research Berlin (
  • Nalls MA; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.
  • Ridge PG; Departments of Biology, Neuroscience, Brigham Young University, Provo, UT, USA.
  • Gibbs JR; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.
  • Lupton MK; King's College London Institute of Psychiatry, London, UK; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
  • Troakes C; King's College London Institute of Psychiatry, London, UK.
  • Lunnon K; King's College London Institute of Psychiatry, London, UK; Institute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter, Devon, UK.
  • Al-Sarraj S; King's College London Institute of Psychiatry, London, UK.
  • Brown KS; Translation Cell Sciences-Human Genetics, School of Life Sciences, Queens Medical Centre, University of Nottingham, Nottingham, UK.
  • Medway C; Translation Cell Sciences-Human Genetics, School of Life Sciences, Queens Medical Centre, University of Nottingham, Nottingham, UK.
  • Lord J; Translation Cell Sciences-Human Genetics, School of Life Sciences, Queens Medical Centre, University of Nottingham, Nottingham, UK.
  • Turton J; Translation Cell Sciences-Human Genetics, School of Life Sciences, Queens Medical Centre, University of Nottingham, Nottingham, UK.
  • Bras J; Department of Molecular Neuroscience, Institute of Neurology, University College London, London, UK; Department of Medical Sciences, Institute of Biomedicine-iBiMED, University of Aveiro, Aveiro, Portugal; UK Dementia Research Institute at UCL (UK DRI), London, UK.
  • Blumenau S; Department of Experimental Neurology, Center for Stroke Research Berlin (CSB), Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
  • Thielke M; Department of Experimental Neurology, Center for Stroke Research Berlin (CSB), Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
  • Josties C; Department of Experimental Neurology, Center for Stroke Research Berlin (CSB), Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
  • Freyer D; Department of Experimental Neurology, Center for Stroke Research Berlin (CSB), Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
  • Dietrich A; Neurodegenerative Diseases, Robert-Koch-Institut, Berlin, Germany.
  • Hammer M; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.
  • Baier M; Neurodegenerative Diseases, Robert-Koch-Institut, Berlin, Germany.
  • Dirnagl U; Department of Experimental Neurology, Center for Stroke Research Berlin (CSB), Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
  • Morgan K; Translation Cell Sciences-Human Genetics, School of Life Sciences, Queens Medical Centre, University of Nottingham, Nottingham, UK.
  • Powell JF; King's College London Institute of Psychiatry, London, UK.
  • Kauwe JS; Departments of Biology, Neuroscience, Brigham Young University, Provo, UT, USA; Department of Neuroscience, Brigham Young University, Provo, UT, USA.
  • Cruchaga C; Division of Biology and Biomedical Sciences, Washington University, St. Louis, MO, USA.
  • Goate AM; Icahn School of Medicine at Mount Sinai, Icahn Medical Institute, New York, NY, USA.
  • Singleton AB; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.
  • Guerreiro R; Department of Molecular Neuroscience, Institute of Neurology, University College London, London, UK; Department of Medical Sciences, Institute of Biomedicine-iBiMED, University of Aveiro, Aveiro, Portugal; UK Dementia Research Institute at UCL (UK DRI), London, UK.
  • Hodges A; King's College London Institute of Psychiatry, London, UK.
  • Hardy J; Reta Lila, Weston Research Laboratories, Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK.
Neurobiol Aging ; 66: 179.e17-179.e29, 2018 06.
Article em En | MEDLINE | ID: mdl-29544907
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores de Fator Estimulador das Colônias de Granulócitos e Macrófagos / Estudos de Associação Genética / Doença de Alzheimer / Receptor Notch3 / Leucodistrofia Metacromática / Mutação Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Neurobiol Aging Ano de publicação: 2018 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores de Fator Estimulador das Colônias de Granulócitos e Macrófagos / Estudos de Associação Genética / Doença de Alzheimer / Receptor Notch3 / Leucodistrofia Metacromática / Mutação Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Neurobiol Aging Ano de publicação: 2018 Tipo de documento: Article