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Translational Pharmacokinetic/Pharmacodynamic Characterization and Target-Mediated Drug Disposition Modeling of an Anti-Tissue Factor Pathway Inhibitor Antibody, PF-06741086.
Parng, Chuenlei; Singh, Pratap; Pittman, Debra D; Wright, Katherine; Leary, Beth; Patel-Hett, Sunita; Rakhe, Swapnil; Stejskal, James; Peraza, Marjorie; Dufield, Dawn; Murphy, John E; Webster, Rob.
Afiliação
  • Parng C; Pfizer Biomedicine Design, Cambridge, Massachusetts 02139. Electronic address: chuenlei.parng@pfizer.com.
  • Singh P; Pfizer Biomedicine Design, Cambridge, Massachusetts 02139.
  • Pittman DD; Pfizer Rare Disease Research Unit, Hematology, Cambridge, Massachusetts 02139.
  • Wright K; Pfizer Biomedicine Design, Cambridge, Massachusetts 02139.
  • Leary B; Pfizer Biomedicine Design, Cambridge, Massachusetts 02139.
  • Patel-Hett S; Pfizer Rare Disease Research Unit, Hematology, Cambridge, Massachusetts 02139.
  • Rakhe S; Pfizer Rare Disease Research Unit, Hematology, Cambridge, Massachusetts 02139.
  • Stejskal J; Pfizer Drug Safety Research and Development, Cambridge, Massachusetts 02139.
  • Peraza M; Pfizer Drug Safety Research and Development, Cambridge, Massachusetts 02139.
  • Dufield D; Pfizer Biomedicine Design, Cambridge, Massachusetts 02139.
  • Murphy JE; Pfizer Rare Disease Research Unit, Hematology, Cambridge, Massachusetts 02139.
  • Webster R; Pfizer Biomedicine Design, Cambridge, Massachusetts 02139.
J Pharm Sci ; 107(7): 1995-2004, 2018 07.
Article em En | MEDLINE | ID: mdl-29571739
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Coagulação Sanguínea / Hemostáticos / Lipoproteínas / Anticorpos Monoclonais Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: J Pharm Sci Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Coagulação Sanguínea / Hemostáticos / Lipoproteínas / Anticorpos Monoclonais Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: J Pharm Sci Ano de publicação: 2018 Tipo de documento: Article