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IMGN779, a Novel CD33-Targeting Antibody-Drug Conjugate with DNA-Alkylating Activity, Exhibits Potent Antitumor Activity in Models of AML.
Kovtun, Yelena; Noordhuis, Paul; Whiteman, Kathleen R; Watkins, Krystal; Jones, Gregory E; Harvey, Lauren; Lai, Katharine C; Portwood, Scott; Adams, Sharlene; Sloss, Callum M; Schuurhuis, Gerrit Jan; Ossenkoppele, Gert; Wang, Eunice S; Pinkas, Jan.
Afiliação
  • Kovtun Y; ImmunoGen, Inc., Waltham, Massachusetts. Yelena.kovtun@immunogen.com.
  • Noordhuis P; Department of Hematology, VU University Medical Center, Amsterdam, the Netherlands.
  • Whiteman KR; ImmunoGen, Inc., Waltham, Massachusetts.
  • Watkins K; ImmunoGen, Inc., Waltham, Massachusetts.
  • Jones GE; ImmunoGen, Inc., Waltham, Massachusetts.
  • Harvey L; ImmunoGen, Inc., Waltham, Massachusetts.
  • Lai KC; ImmunoGen, Inc., Waltham, Massachusetts.
  • Portwood S; Department of Medicine, Roswell Park Cancer Institute, Buffalo, New York.
  • Adams S; ImmunoGen, Inc., Waltham, Massachusetts.
  • Sloss CM; ImmunoGen, Inc., Waltham, Massachusetts.
  • Schuurhuis GJ; Department of Hematology, VU University Medical Center, Amsterdam, the Netherlands.
  • Ossenkoppele G; Department of Hematology, VU University Medical Center, Amsterdam, the Netherlands.
  • Wang ES; Department of Medicine, Roswell Park Cancer Institute, Buffalo, New York.
  • Pinkas J; ImmunoGen, Inc., Waltham, Massachusetts.
Mol Cancer Ther ; 17(6): 1271-1279, 2018 06.
Article em En | MEDLINE | ID: mdl-29588393
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Imunoconjugados / Antineoplásicos Alquilantes / Lectina 3 Semelhante a Ig de Ligação ao Ácido Siálico / Antineoplásicos Imunológicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Mol Cancer Ther Assunto da revista: ANTINEOPLASICOS Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Imunoconjugados / Antineoplásicos Alquilantes / Lectina 3 Semelhante a Ig de Ligação ao Ácido Siálico / Antineoplásicos Imunológicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Mol Cancer Ther Assunto da revista: ANTINEOPLASICOS Ano de publicação: 2018 Tipo de documento: Article