Targeted Proteomics Guided by Label-free Quantitative Proteome Analysis in Saliva Reveal Transition Signatures from Health to Periodontal Disease.

Bostanci, Nagihan; Selevsek, Nathalie; Wolski, Witold; Grossmann, Jonas; Bao, Kai; Wahlander, Asa; Trachsel, Christian; Schlapbach, Ralph; Öztürk, Veli Özgen; Afacan, Beral; Emingil, Gulnur; Belibasakis, Georgios N

Bostanci, Nagihan; Selevsek, Nathalie; Wolski, Witold; Grossmann, Jonas; Bao, Kai; Wahlander, Asa; Trachsel, Christian; Schlapbach, Ralph; Öztürk, Veli Özgen; Afacan, Beral; Emingil, Gulnur; Belibasakis, Georgios N.

Afiliação

Bostanci N; From the Division of Oral Diseases, Department of Dental Medicine, Karolinska Institutet, Stockholm, Sweden; nagihan.bostanci@ki.se.
Selevsek N; §Functional Genomics Center Zürich, University of Zürich/ETH Zürich, Zürich, Switzerland.
Wolski W; §Functional Genomics Center Zürich, University of Zürich/ETH Zürich, Zürich, Switzerland.
Grossmann J; §Functional Genomics Center Zürich, University of Zürich/ETH Zürich, Zürich, Switzerland.
Bao K; From the Division of Oral Diseases, Department of Dental Medicine, Karolinska Institutet, Stockholm, Sweden.
Wahlander A; ¶AstraZeneca Translational Biomarkers and Bioanalysis, Drug Safety and Metabolism, Innovative Medicines, Mölndal, Sweden.
Trachsel C; §Functional Genomics Center Zürich, University of Zürich/ETH Zürich, Zürich, Switzerland.
Schlapbach R; §Functional Genomics Center Zürich, University of Zürich/ETH Zürich, Zürich, Switzerland.
Öztürk VÖ; âDepartment of Periodontology, School of Dentistry, Adnan Menderes University, Aydin, Turkey.
Afacan B; âDepartment of Periodontology, School of Dentistry, Adnan Menderes University, Aydin, Turkey.
Emingil G; **Department of Periodontology, School of Dentistry, Ege University, Izmir, Turkey.
Belibasakis GN; From the Division of Oral Diseases, Department of Dental Medicine, Karolinska Institutet, Stockholm, Sweden.

Mol Cell Proteomics ; 17(7): 1392-1409, 2018 07.

Article em En | MEDLINE | ID: mdl-29610270

Assuntos

Doenças Periodontais/metabolismo; Proteoma/metabolismo; Proteômica/métodos; Saliva/metabolismo; Proteínas e Peptídeos Salivares/metabolismo; Adulto; Área Sob a Curva; Biomarcadores/metabolismo; Humanos; Pessoa de Meia-Idade; Mapas de Interação de Proteínas; Reprodutibilidade dos Testes; Coloração e Rotulagem; Adulto Jovem

Palavras-chave

Biofluids*; Biomarker: Diagnostic; Biomarker: Prognostic; Diagnostic; Host-Pathogen Interaction; Infectious disease; Inflammation; Inflammatory response; Label-free quantification; Selected reaction monitoring; agressive periodontitis; chronic periodontitis; oral biofluids; periodontal disease; saliva

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Periodontais / Saliva / Proteínas e Peptídeos Salivares / Proteoma / Proteômica Tipo de estudo: Prognostic_studies / Screening_studies Limite: Adult / Humans / Middle aged Idioma: En Revista: Mol Cell Proteomics Assunto da revista: BIOLOGIA MOLECULAR / BIOQUIMICA Ano de publicação: 2018 Tipo de documento: Article

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