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Discovery of novel Methylsulfonyl phenyl derivatives as potent human Cyclooxygenase-2 inhibitors with effective anticonvulsant action: Design, synthesis, in-silico, in-vitro and in-vivo evaluation.
Mishra, Chandra Bhushan; Kumari, Shikha; Prakash, Amresh; Yadav, Rajesh; Tiwari, Ankit Kumar; Pandey, Preeti; Tiwari, Manisha.
Afiliação
  • Mishra CB; Bio-Organic Chemistry Laboratory, Dr. B. R. Ambedkar Center for Biomedical Research, University of Delhi, Delhi, 110007, India.
  • Kumari S; Bio-Organic Chemistry Laboratory, Dr. B. R. Ambedkar Center for Biomedical Research, University of Delhi, Delhi, 110007, India.
  • Prakash A; School of Computational and Integrative Sciences, Jawaharlal Nehru University, New Delhi, India.
  • Yadav R; Bio-Organic Chemistry Laboratory, Dr. B. R. Ambedkar Center for Biomedical Research, University of Delhi, Delhi, 110007, India.
  • Tiwari AK; Bio-Organic Chemistry Laboratory, Dr. B. R. Ambedkar Center for Biomedical Research, University of Delhi, Delhi, 110007, India.
  • Pandey P; School of Computational and Integrative Sciences, Jawaharlal Nehru University, New Delhi, India.
  • Tiwari M; Bio-Organic Chemistry Laboratory, Dr. B. R. Ambedkar Center for Biomedical Research, University of Delhi, Delhi, 110007, India. Electronic address: mtiwari07@gmail.com.
Eur J Med Chem ; 151: 520-532, 2018 May 10.
Article em En | MEDLINE | ID: mdl-29655084
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Convulsões / Inibidores de Ciclo-Oxigenase 2 / Anticonvulsivantes Limite: Animals / Humans / Male Idioma: En Revista: Eur J Med Chem Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Índia
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Convulsões / Inibidores de Ciclo-Oxigenase 2 / Anticonvulsivantes Limite: Animals / Humans / Male Idioma: En Revista: Eur J Med Chem Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Índia