A Photorearrangement To Construct the ABDE Tetracyclic Core of Palau'amine.
Org Lett
; 20(9): 2615-2619, 2018 05 04.
Article
em En
| MEDLINE
| ID: mdl-29667828
ABSTRACT
A synthesis of the ABDE tetracyclic carbon core of palau'amine was achieved in 9 steps from commercial materials. The core's most notable feature, a highly strained trans cyclopenta[ c]pyrrolidine, was obtained in high yield using a ring contraction strategy starting from a much less strained trans bicyclic lactam derivative that is accessible in only 7 steps.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Org Lett
Assunto da revista:
BIOQUIMICA
Ano de publicação:
2018
Tipo de documento:
Article