Inhibition of UVB-induced pro-inflammatory cytokines and MMP expression by Zanthoxylum rhetsa bark extract and its active constituent hesperidin.

Santhanam, Ramesh Kumar; Fakurazi, Sharida; Ahmad, Syahida; Abas, Faridah; Ismail, Intan Safinar; Rukayadi, Yaya; Akhtar, Muhammad Tayyab; Shaari, Khozirah

Santhanam, Ramesh Kumar; Fakurazi, Sharida; Ahmad, Syahida; Abas, Faridah; Ismail, Intan Safinar; Rukayadi, Yaya; Akhtar, Muhammad Tayyab; Shaari, Khozirah.

Afiliação

Santhanam RK; Laboratory of Natural Products, Institute of Bioscience, Universiti Putra Malaysia, 43400 UPM, Serdang, Selangor, Malaysia.
Fakurazi S; Tianjin Key Laboratory for Modern Drug Delivery & High Efficiency, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin, 300072, China.
Ahmad S; Laboratory of Vaccine and Immunotherapeutics, Institute of Bioscience, 43400 UPM, Serdang, Selangor, Malaysia.
Abas F; Department of Human Anatomy, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM, Serdang, Selangor, Malaysia.
Ismail IS; Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, 43400 UPM, Serdang, Selangor, Malaysia.
Rukayadi Y; Laboratory of Natural Products, Institute of Bioscience, Universiti Putra Malaysia, 43400 UPM, Serdang, Selangor, Malaysia.
Akhtar MT; Laboratory of Natural Products, Institute of Bioscience, Universiti Putra Malaysia, 43400 UPM, Serdang, Selangor, Malaysia.
Shaari K; Laboratory of Natural Products, Institute of Bioscience, Universiti Putra Malaysia, 43400 UPM, Serdang, Selangor, Malaysia.

Phytother Res ; 32(8): 1608-1616, 2018 Aug.

Article em En | MEDLINE | ID: mdl-29672974

Assuntos

Citocinas/metabolismo; Hesperidina/farmacologia; Metaloproteinases da Matriz/metabolismo; Casca de Planta/química; Extratos Vegetais/farmacologia; Raios Ultravioleta; Zanthoxylum/química; Células Cultivadas; Fibroblastos/efeitos dos fármacos; Fibroblastos/efeitos da radiação; Humanos; Interleucina-1beta/metabolismo; Interleucina-6/metabolismo; Malásia; Metaloproteinase 1 da Matriz/metabolismo; Metaloproteinase 3 da Matriz/metabolismo; Metaloproteinase 9 da Matriz/metabolismo; Inibidores de Metaloproteinases de Matriz/farmacologia; NF-kappa B/metabolismo; Elastase Pancreática/antagonistas & inibidores; Fator de Necrose Tumoral alfa/metabolismo

Palavras-chave

UVB protection; Zanthoxylum rhetsa; anticollagenase; antielastase; hesperidin; photo aging

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Raios Ultravioleta / Extratos Vegetais / Citocinas / Metaloproteinases da Matriz / Casca de Planta / Zanthoxylum / Hesperidina Limite: Humans País/Região como assunto: Asia Idioma: En Revista: Phytother Res Assunto da revista: TERAPIAS COMPLEMENTARES Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Malásia

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