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RNAi screening identifies a mechanosensitive ROCK-JAK2-STAT3 network central to myofibroblast activation.
Oh, Raymond S; Haak, Andrew J; Smith, Karry M J; Ligresti, Giovanni; Choi, Kyoung Moo; Xie, Tiao; Wang, Shaohua; Walters, Paula R; Thompson, Michael A; Freeman, Michelle R; Manlove, Logan J; Chu, Vivian M; Feghali-Bostwick, Carol; Roden, Anja C; Schymeinsky, Jürgen; Pabelick, Christina M; Prakash, Y S; Vassallo, Robert; Tschumperlin, Daniel J.
Afiliação
  • Oh RS; Department of Environmental Health, Harvard School of Public Health, Boston, MA 02115, USA r.sangin.oh@gmail.com haak.andrew@mayo.edu.
  • Haak AJ; Department of Physiology & Biomedical Engineering, Mayo Clinic, Rochester, MN 55905, USA r.sangin.oh@gmail.com haak.andrew@mayo.edu.
  • Smith KMJ; Department of Physiology & Biomedical Engineering, Mayo Clinic, Rochester, MN 55905, USA.
  • Ligresti G; Department of Physiology & Biomedical Engineering, Mayo Clinic, Rochester, MN 55905, USA.
  • Choi KM; Department of Physiology & Biomedical Engineering, Mayo Clinic, Rochester, MN 55905, USA.
  • Xie T; Image and Data Analysis Core, Harvard Medical School, Boston, MA 02115, USA.
  • Wang S; Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN 55905, USA.
  • Walters PR; Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN 55905, USA.
  • Thompson MA; Departments of Anesthesiology and Physiology & Biomedical Engineering, Mayo Clinic, Rochester, MN 55905, USA.
  • Freeman MR; Departments of Anesthesiology and Physiology & Biomedical Engineering, Mayo Clinic, Rochester, MN 55905, USA.
  • Manlove LJ; Departments of Anesthesiology and Physiology & Biomedical Engineering, Mayo Clinic, Rochester, MN 55905, USA.
  • Chu VM; Department of Physiology & Biomedical Engineering, Mayo Clinic, Rochester, MN 55905, USA.
  • Feghali-Bostwick C; Division of Rheumatology and Immunology, Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.
  • Roden AC; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA.
  • Schymeinsky J; Department of Respiratory Diseases Research, Boehringer Ingelheim Pharma GmbH & Co. KG, 88397 Biberach, Germany.
  • Pabelick CM; Departments of Anesthesiology and Physiology & Biomedical Engineering, Mayo Clinic, Rochester, MN 55905, USA.
  • Prakash YS; Departments of Anesthesiology and Physiology & Biomedical Engineering, Mayo Clinic, Rochester, MN 55905, USA.
  • Vassallo R; Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN 55905, USA.
  • Tschumperlin DJ; Department of Physiology & Biomedical Engineering, Mayo Clinic, Rochester, MN 55905, USA.
J Cell Sci ; 131(10)2018 05 15.
Article em En | MEDLINE | ID: mdl-29678906
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fibrose Pulmonar / Interferência de RNA / Fator de Transcrição STAT3 / Janus Quinase 2 / Quinases Associadas a rho / Miofibroblastos Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Limite: Animals / Female / Humans Idioma: En Revista: J Cell Sci Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fibrose Pulmonar / Interferência de RNA / Fator de Transcrição STAT3 / Janus Quinase 2 / Quinases Associadas a rho / Miofibroblastos Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Limite: Animals / Female / Humans Idioma: En Revista: J Cell Sci Ano de publicação: 2018 Tipo de documento: Article