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Substrate-bound outward-open structure of a Na+-coupled sialic acid symporter reveals a new Na+ site.
Wahlgren, Weixiao Y; Dunevall, Elin; North, Rachel A; Paz, Aviv; Scalise, Mariafrancesca; Bisignano, Paola; Bengtsson-Palme, Johan; Goyal, Parveen; Claesson, Elin; Caing-Carlsson, Rhawnie; Andersson, Rebecka; Beis, Konstantinos; Nilsson, Ulf J; Farewell, Anne; Pochini, Lorena; Indiveri, Cesare; Grabe, Michael; Dobson, Renwick C J; Abramson, Jeff; Ramaswamy, S; Friemann, Rosmarie.
Afiliação
  • Wahlgren WY; Department of Chemistry and Molecular Biology, University of Gothenburg, Box 462, S-40530, Gothenburg, Sweden. Weixiao.YuanWahlgren@chem.gu.se.
  • Dunevall E; Centre for Antibiotic Resistance Research (CARe) at University of Gothenburg, Box 440, S-40530, Gothenburg, Sweden. Weixiao.YuanWahlgren@chem.gu.se.
  • North RA; Department of Life Sciences, Imperial College London, Exhibition Road, London, South Kensington, SW7 2AZ, UK. Weixiao.YuanWahlgren@chem.gu.se.
  • Paz A; Membrane Protein Lab, Diamond Light Source, Harwell Science and Innovation Campus, Chilton, Oxfordshire, OX11 0DE, UK. Weixiao.YuanWahlgren@chem.gu.se.
  • Scalise M; Rutherford Appleton Laboratory, Research Complex at Harwell, Didcot, Oxfordshire, OX11 0FA, UK. Weixiao.YuanWahlgren@chem.gu.se.
  • Bisignano P; Department of Chemistry and Molecular Biology, University of Gothenburg, Box 462, S-40530, Gothenburg, Sweden.
  • Bengtsson-Palme J; Department of Chemistry and Molecular Biology, University of Gothenburg, Box 462, S-40530, Gothenburg, Sweden.
  • Goyal P; Biomolecular Interaction Centre and School of Biological Sciences, University of Canterbury, Private Bag 4800, Christchurch, 8041, New Zealand.
  • Claesson E; Department of Physiology, David Geffen School of Medicine, University of California, Los Angeles, CA, 90095-1751, USA.
  • Caing-Carlsson R; Department DiBEST (Biologia, Ecologia, Scienze della Terra) Unit of Biochemistry and Molecular Biotechnology, University of Calabria, Via P. Bucci 4C, 87036, Arcavacata di Rende, Italy.
  • Andersson R; Cardiovascular Research Institute, Department of Pharmaceutical Chemistry, University of California, San Francisco, CA, 94158, USA.
  • Beis K; Centre for Antibiotic Resistance Research (CARe) at University of Gothenburg, Box 440, S-40530, Gothenburg, Sweden.
  • Nilsson UJ; Department of Infectious Diseases, Institute for Biomedicine, Sahlgrenska Academy, University of Gothenburg, Box 440, S-40530, Gothenburg, Sweden.
  • Farewell A; Department of Chemistry and Molecular Biology, University of Gothenburg, Box 462, S-40530, Gothenburg, Sweden.
  • Pochini L; Centre for Antibiotic Resistance Research (CARe) at University of Gothenburg, Box 440, S-40530, Gothenburg, Sweden.
  • Indiveri C; Department of Chemistry and Molecular Biology, University of Gothenburg, Box 462, S-40530, Gothenburg, Sweden.
  • Grabe M; Department of Chemistry and Molecular Biology, University of Gothenburg, Box 462, S-40530, Gothenburg, Sweden.
  • Dobson RCJ; Department of Chemistry and Molecular Biology, University of Gothenburg, Box 462, S-40530, Gothenburg, Sweden.
  • Abramson J; Department of Life Sciences, Imperial College London, Exhibition Road, London, South Kensington, SW7 2AZ, UK.
  • Ramaswamy S; Membrane Protein Lab, Diamond Light Source, Harwell Science and Innovation Campus, Chilton, Oxfordshire, OX11 0DE, UK.
  • Friemann R; Rutherford Appleton Laboratory, Research Complex at Harwell, Didcot, Oxfordshire, OX11 0FA, UK.
Nat Commun ; 9(1): 1753, 2018 05 01.
Article em En | MEDLINE | ID: mdl-29717135

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sódio / Transportadores de Ânions Orgânicos / Simportadores Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Suécia

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sódio / Transportadores de Ânions Orgânicos / Simportadores Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Suécia