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CSF1R+ Macrophages Sustain Pancreatic Tumor Growth through T Cell Suppression and Maintenance of Key Gene Programs that Define the Squamous Subtype.
Candido, Juliana B; Morton, Jennifer P; Bailey, Peter; Campbell, Andrew D; Karim, Saadia A; Jamieson, Thomas; Lapienyte, Laura; Gopinathan, Aarthi; Clark, William; McGhee, Ewan J; Wang, Jun; Escorcio-Correia, Monica; Zollinger, Raphael; Roshani, Rozita; Drew, Lisa; Rishi, Loveena; Arkell, Rebecca; Evans, T R Jeffry; Nixon, Colin; Jodrell, Duncan I; Wilkinson, Robert W; Biankin, Andrew V; Barry, Simon T; Balkwill, Frances R; Sansom, Owen J.
Afiliação
  • Candido JB; Barts Cancer Institute, Queen Mary University of London, London EC1M 6BQ, UK.
  • Morton JP; Cancer Research UK Beatson Institute, Glasgow G61 1BD, UK; Institute of Cancer Sciences, University of Glasgow, Glasgow G61 1QH, UK.
  • Bailey P; Institute of Cancer Sciences, University of Glasgow, Glasgow G61 1QH, UK.
  • Campbell AD; Cancer Research UK Beatson Institute, Glasgow G61 1BD, UK.
  • Karim SA; Cancer Research UK Beatson Institute, Glasgow G61 1BD, UK.
  • Jamieson T; Cancer Research UK Beatson Institute, Glasgow G61 1BD, UK.
  • Lapienyte L; Cancer Research UK Beatson Institute, Glasgow G61 1BD, UK.
  • Gopinathan A; Cancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Robinson Way, Cambridge CB2 0RE, UK.
  • Clark W; Cancer Research UK Beatson Institute, Glasgow G61 1BD, UK.
  • McGhee EJ; Cancer Research UK Beatson Institute, Glasgow G61 1BD, UK.
  • Wang J; Barts Cancer Institute, Queen Mary University of London, London EC1M 6BQ, UK.
  • Escorcio-Correia M; Barts Cancer Institute, Queen Mary University of London, London EC1M 6BQ, UK.
  • Zollinger R; Barts Cancer Institute, Queen Mary University of London, London EC1M 6BQ, UK.
  • Roshani R; Barts Cancer Institute, Queen Mary University of London, London EC1M 6BQ, UK.
  • Drew L; Bioscience, Oncology, iMED Biotech Unit, AstraZeneca, Boston, MA, USA.
  • Rishi L; Institute of Cancer Sciences, University of Glasgow, Glasgow G61 1QH, UK.
  • Arkell R; Barts Cancer Institute, Queen Mary University of London, London EC1M 6BQ, UK.
  • Evans TRJ; Cancer Research UK Beatson Institute, Glasgow G61 1BD, UK; Institute of Cancer Sciences, University of Glasgow, Glasgow G61 1QH, UK.
  • Nixon C; Cancer Research UK Beatson Institute, Glasgow G61 1BD, UK.
  • Jodrell DI; Cancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Robinson Way, Cambridge CB2 0RE, UK.
  • Wilkinson RW; MedImmune Ltd, Granta Park, Cambridge CB21 6GH, UK.
  • Biankin AV; Institute of Cancer Sciences, University of Glasgow, Glasgow G61 1QH, UK.
  • Barry ST; Bioscience, Oncology, iMED Biotech Unit, AstraZeneca, Cambridge, UK.
  • Balkwill FR; Barts Cancer Institute, Queen Mary University of London, London EC1M 6BQ, UK.
  • Sansom OJ; Cancer Research UK Beatson Institute, Glasgow G61 1BD, UK; Institute of Cancer Sciences, University of Glasgow, Glasgow G61 1QH, UK. Electronic address: o.sansom@beatson.gla.ac.uk.
Cell Rep ; 23(5): 1448-1460, 2018 05 01.
Article em En | MEDLINE | ID: mdl-29719257
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Linfócitos T / Receptores de Fator Estimulador das Colônias de Granulócitos e Macrófagos / Modelos Imunológicos / Carcinoma Ductal Pancreático / Macrófagos / Proteínas de Neoplasias Tipo de estudo: Prognostic_studies Limite: Adult / Animals / Female / Humans / Male Idioma: En Revista: Cell Rep Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Linfócitos T / Receptores de Fator Estimulador das Colônias de Granulócitos e Macrófagos / Modelos Imunológicos / Carcinoma Ductal Pancreático / Macrófagos / Proteínas de Neoplasias Tipo de estudo: Prognostic_studies Limite: Adult / Animals / Female / Humans / Male Idioma: En Revista: Cell Rep Ano de publicação: 2018 Tipo de documento: Article