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Novel FGFR2-INA fusion identified in two low-grade mixed neuronal-glial tumors drives oncogenesis via MAPK and PI3K/mTOR pathway activation.
Jain, Payal; Surrey, Lea F; Straka, Joshua; Luo, Minjie; Lin, Fumin; Harding, Brian; Resnick, Adam C; Storm, Phillip B; Buccoliero, Anna Maria; Santi, Mariarita; Li, Marilyn M; Waanders, Angela J.
Afiliação
  • Jain P; Center for Data Driven Discovery in Biomedicine, Children's Hospital of Philadelphia, 3501 Civic Center Boulevard, Philadelphia, PA, 19104, USA.
  • Surrey LF; Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.
  • Straka J; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Luo M; Center for Data Driven Discovery in Biomedicine, Children's Hospital of Philadelphia, 3501 Civic Center Boulevard, Philadelphia, PA, 19104, USA.
  • Lin F; Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.
  • Harding B; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Resnick AC; Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.
  • Storm PB; Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.
  • Buccoliero AM; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Santi M; Center for Data Driven Discovery in Biomedicine, Children's Hospital of Philadelphia, 3501 Civic Center Boulevard, Philadelphia, PA, 19104, USA.
  • Li MM; Department of Neurosurgery, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.
  • Waanders AJ; Meyer Children's Hospital, Florence, Italy.
Acta Neuropathol ; 136(1): 167-169, 2018 07.
Article em En | MEDLINE | ID: mdl-29767381
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Transdução de Sinais / Receptor Tipo 2 de Fator de Crescimento de Fibroblastos / Carcinogênese / Glioma / Proteínas de Filamentos Intermediários Tipo de estudo: Prognostic_studies Limite: Humans / Male Idioma: En Revista: Acta Neuropathol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Transdução de Sinais / Receptor Tipo 2 de Fator de Crescimento de Fibroblastos / Carcinogênese / Glioma / Proteínas de Filamentos Intermediários Tipo de estudo: Prognostic_studies Limite: Humans / Male Idioma: En Revista: Acta Neuropathol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos