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Early identification of unusually clustered mutations and root causes in therapeutic antibody development.
Qian, Yueming; Chen, Zhiqiang; Huang, Xin; Wang, Xuning; Xu, Xuankuo; Kirov, Stefan; Ludwig, Richard; Qian, Nan-Xin; Ravi, Kandasamy; Tao, Li; Borys, Michael C; Li, Zheng Jian.
Afiliação
  • Qian Y; Product Development, Global Product Development and Supply, Bristol-Myers Squibb Company, Devens, Massachusetts.
  • Chen Z; Product Development, Global Product Development and Supply, Bristol-Myers Squibb Company, Devens, Massachusetts.
  • Huang X; Research and Development, Bristol-Myers Squibb Company, Pennington, New Jersey.
  • Wang X; Research and Development, Bristol-Myers Squibb Company, Pennington, New Jersey.
  • Xu X; Product Development, Global Product Development and Supply, Bristol-Myers Squibb Company, Devens, Massachusetts.
  • Kirov S; Research and Development, Bristol-Myers Squibb Company, Pennington, New Jersey.
  • Ludwig R; Product Development, Global Product Development and Supply, Bristol-Myers Squibb Company, Pennington, New Jersey.
  • Qian NX; Product Development, Global Product Development and Supply, Bristol-Myers Squibb Company, Devens, Massachusetts.
  • Ravi K; Research and Development, Bristol-Myers Squibb Company, Pennington, New Jersey.
  • Tao L; Product Development, Global Product Development and Supply, Bristol-Myers Squibb Company, Pennington, New Jersey.
  • Borys MC; Product Development, Global Product Development and Supply, Bristol-Myers Squibb Company, Devens, Massachusetts.
  • Li ZJ; Product Development, Global Product Development and Supply, Bristol-Myers Squibb Company, Devens, Massachusetts.
Biotechnol Bioeng ; 115(9): 2377-2382, 2018 09.
Article em En | MEDLINE | ID: mdl-29777592

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Recombinantes / Vetores Genéticos / Fatores Imunológicos / Anticorpos / Mutação Tipo de estudo: Diagnostic_studies / Etiology_studies / Prognostic_studies Limite: Animals Idioma: En Revista: Biotechnol Bioeng Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Recombinantes / Vetores Genéticos / Fatores Imunológicos / Anticorpos / Mutação Tipo de estudo: Diagnostic_studies / Etiology_studies / Prognostic_studies Limite: Animals Idioma: En Revista: Biotechnol Bioeng Ano de publicação: 2018 Tipo de documento: Article