Autoregulation of the human splice factor kinase CLK1 through exon skipping and intron retention.

Uzor, Simon; Zorzou, Panagiota; Bowler, Elizabeth; Porazinski, Sean; Wilson, Ian; Ladomery, Michael

Uzor, Simon; Zorzou, Panagiota; Bowler, Elizabeth; Porazinski, Sean; Wilson, Ian; Ladomery, Michael.

Afiliação

Uzor S; Faculty of Health and Applied Sciences, University of the West of England, Coldharbour Lane, Frenchay, Bristol BS16 1QY, United Kingdom.
Zorzou P; Faculty of Health and Applied Sciences, University of the West of England, Coldharbour Lane, Frenchay, Bristol BS16 1QY, United Kingdom.
Bowler E; Faculty of Health and Applied Sciences, University of the West of England, Coldharbour Lane, Frenchay, Bristol BS16 1QY, United Kingdom.
Porazinski S; Faculty of Health and Applied Sciences, University of the West of England, Coldharbour Lane, Frenchay, Bristol BS16 1QY, United Kingdom.
Wilson I; Faculty of Health and Applied Sciences, University of the West of England, Coldharbour Lane, Frenchay, Bristol BS16 1QY, United Kingdom.
Ladomery M; Faculty of Health and Applied Sciences, University of the West of England, Coldharbour Lane, Frenchay, Bristol BS16 1QY, United Kingdom. Electronic address: Michael.Ladomery@uwe.ac.uk.

Gene ; 670: 46-54, 2018 Sep 05.

Article em En | MEDLINE | ID: mdl-29802995

Assuntos

Processamento Alternativo; Neoplasias/genética; Proteínas Serina-Treonina Quinases/genética; Proteínas Tirosina Quinases/genética; Estresse Fisiológico; Tiazóis/farmacologia; Processamento Alternativo/efeitos dos fármacos; Linhagem Celular Tumoral; Éxons; Regulação da Expressão Gênica; Células HL-60; Harmina/farmacologia; Homeostase; Temperatura Alta; Humanos; Íntrons; Pressão Osmótica

Palavras-chave

Alternative splicing; CDC-like protein kinases; CLK1; CLK1 inhibitor TG003; Cassette exons; Detained introns; Harmine; Intron retention

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estresse Fisiológico / Tiazóis / Proteínas Tirosina Quinases / Proteínas Serina-Treonina Quinases / Processamento Alternativo / Neoplasias Limite: Humans Idioma: En Revista: Gene Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Reino Unido

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google