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Identification of compounds acting as negative allosteric modulators of the LPA1 receptor.
Ellery, Jonathan; Dickson, Louise; Cheung, Toni; Ciuclan, Loredana; Bunyard, Peter; Mack, Stephen; Buffham, William J; Farnaby, William; Mitchell, Philip; Brown, Daniel; Isaacs, Richard; Barnes, Matt.
Afiliação
  • Ellery J; Takeda Cambridge Ltd., 418 Cambridge Science Park, Cambridge, Cambridgeshire CB4 0PZ, UK. Electronic address: elleryjonathan@gmail.com.
  • Dickson L; Takeda Cambridge Ltd., 418 Cambridge Science Park, Cambridge, Cambridgeshire CB4 0PZ, UK; Cerevance, 418 Cambridge Science Park, Cambridge, Cambridgeshire CB4 0PZ, UK. Electronic address: louise.dickson@cerevance.com.
  • Cheung T; Takeda Cambridge Ltd., 418 Cambridge Science Park, Cambridge, Cambridgeshire CB4 0PZ, UK; Cerevance, 418 Cambridge Science Park, Cambridge, Cambridgeshire CB4 0PZ, UK. Electronic address: toni.cheung@cerevance.com.
  • Ciuclan L; Takeda Cambridge Ltd., 418 Cambridge Science Park, Cambridge, Cambridgeshire CB4 0PZ, UK; Study Enterprise, Early Clinical Development, IMED Biotech Unit, AstraZeneca, Cambridge, UK. Electronic address: loredana.ciuclan@astrazeneca.com.
  • Bunyard P; Takeda Cambridge Ltd., 418 Cambridge Science Park, Cambridge, Cambridgeshire CB4 0PZ, UK; Redx Immunology, Block 33, Mereside, Alderley Park, Alderley Edge, Macclesfield SK10 4TG, UK. Electronic address: peterbunyard@googlemail.com.
  • Mack S; Takeda Cambridge Ltd., 418 Cambridge Science Park, Cambridge, Cambridgeshire CB4 0PZ, UK; Convergence Pharmaceuticals, B900, Babraham Research Campus, Babraham, Cambridgeshire CB22 3AT, UK. Electronic address: srmdjm@gmail.com.
  • Buffham WJ; Takeda Cambridge Ltd., 418 Cambridge Science Park, Cambridge, Cambridgeshire CB4 0PZ, UK; Convergence Pharmaceuticals, B900, Babraham Research Campus, Babraham, Cambridgeshire CB22 3AT, UK. Electronic address: willbuffham@gmail.com.
  • Farnaby W; Takeda Cambridge Ltd., 418 Cambridge Science Park, Cambridge, Cambridgeshire CB4 0PZ, UK; School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK. Electronic address: w.farnaby@dundee.ac.uk.
  • Mitchell P; Takeda Cambridge Ltd., 418 Cambridge Science Park, Cambridge, Cambridgeshire CB4 0PZ, UK; Charles River Discovery Research Services UK Limited, Robinson Building, Chesterford Research Park, Saffron Walden, Essex CB10 1XL, UK. Electronic address: Philip.Mitchell@crl.com.
  • Brown D; Molecular Sensing Inc., 111 10th Ave. S. Suite 110, Nashville, TN, USA; Albany Molecular Research Inc., The Conventus Building, 1001 Main Street, Buffalo, NY 14203, USA. Electronic address: daniel.brown@amriglobal.com.
  • Isaacs R; Molecular Sensing Inc., 111 10th Ave. S. Suite 110, Nashville, TN, USA; Creoptix Inc., 100 Franklin St Fl7, Boston, MA 02110, USA. Electronic address: jisaacs@creoptix.com.
  • Barnes M; Takeda Cambridge Ltd., 418 Cambridge Science Park, Cambridge, Cambridgeshire CB4 0PZ, UK; Heptares Therapeutics Ltd., BioPark, Broadwater Road, Welwyn Garden City, Hertfordshire AL7 3AX, UK. Electronic address: matt.barnes@heptares.com.
Eur J Pharmacol ; 833: 8-15, 2018 Aug 15.
Article em En | MEDLINE | ID: mdl-29807028
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxazóis / Benzamidas / Benzoatos / Ciclopropanos / Receptores de Ácidos Lisofosfatídicos / Indenos Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals Idioma: En Revista: Eur J Pharmacol Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxazóis / Benzamidas / Benzoatos / Ciclopropanos / Receptores de Ácidos Lisofosfatídicos / Indenos Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals Idioma: En Revista: Eur J Pharmacol Ano de publicação: 2018 Tipo de documento: Article