Epigenetic anticancer agents cause HMGB1 release in vivo.
Oncoimmunology
; 7(6): e1431090, 2018.
Article
em En
| MEDLINE
| ID: mdl-29872561
ABSTRACT
A systematic search for anticancer agents that may induce the release of high mobility group box 1 (HMGB1) protein from cells into the extracellular space has led to the identification of several drugs capable of elevating plasma HMGB1 levels in vivo, in mice. Such agents include bona-fide immunogenic cell death inducers such as oxaliplatin, as well as a series of epigenetic modifiers, namely azacitidine, decitabine, and suberoylanilide hydroxamic acid (SAHA).
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Oncoimmunology
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
França