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Safety and efficacy of upadacitinib in patients with active rheumatoid arthritis refractory to biologic disease-modifying anti-rheumatic drugs (SELECT-BEYOND): a double-blind, randomised controlled phase 3 trial.
Genovese, Mark C; Fleischmann, Roy; Combe, Bernard; Hall, Stephen; Rubbert-Roth, Andrea; Zhang, Ying; Zhou, Yijie; Mohamed, Mohamed-Eslam F; Meerwein, Sebastian; Pangan, Aileen L.
Afiliação
  • Genovese MC; Division of Immunology and Rheumatology, Stanford University School of Medicine, Palo Alto, CA, USA. Electronic address: genovese@stanford.edu.
  • Fleischmann R; University of Texas Southwestern, Metroplex Clinical Research Center, Dallas, Texas, USA.
  • Combe B; Department of Rheumatology, CHU Montpellier, Université de Montpellier, Montpellier, France.
  • Hall S; Department of Medicine, Monash University, Cabrini Health and Emeritus Research, Malvern, VIC, Australia.
  • Rubbert-Roth A; Kantonsspital St Gallen, St Gallen, Switzerland.
  • Zhang Y; AbbVie Inc, North Chicago, IL, USA.
  • Zhou Y; AbbVie Inc, North Chicago, IL, USA.
  • Mohamed MF; AbbVie Inc, North Chicago, IL, USA.
  • Meerwein S; AbbVie Deutschland, Ludwigshafen, Germany.
  • Pangan AL; AbbVie Inc, North Chicago, IL, USA.
Lancet ; 391(10139): 2513-2524, 2018 06 23.
Article em En | MEDLINE | ID: mdl-29908670

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Inibidores de Janus Quinases / Compostos Heterocíclicos com 3 Anéis Tipo de estudo: Clinical_trials Limite: Aged / Humans / Middle aged Idioma: En Revista: Lancet Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Inibidores de Janus Quinases / Compostos Heterocíclicos com 3 Anéis Tipo de estudo: Clinical_trials Limite: Aged / Humans / Middle aged Idioma: En Revista: Lancet Ano de publicação: 2018 Tipo de documento: Article