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Identification of the Natural Product Rotihibin A as a TOR Kinase Signaling Inhibitor by Unbiased Transcriptional Profiling.
Halder, Vivek; Oeljeklaus, Julian; Heilmann, Geronimo; Krahn, Jan H; Liu, Yanlin; Xiong, Yan; Schlicht, Markus; Schillinger, Jasmin; Kracher, Barbara; Ehrmann, Michael; Kombrink, Erich; Kaschani, Farnusch; Kaiser, Markus.
Afiliação
  • Halder V; Chemical Biology, Zentrum für Medizinische Biotechnologie, Universität Duisburg-Essen, Universitätsstrasse 2, 45117, Essen, Germany.
  • Oeljeklaus J; Chemical Biology Laboratory, Max-Planck-Institute for Plant Breeding Research, Carl-von-Linnè-Weg 10, 50829, Köln, Germany.
  • Heilmann G; Chemical Biology, Zentrum für Medizinische Biotechnologie, Universität Duisburg-Essen, Universitätsstrasse 2, 45117, Essen, Germany.
  • Krahn JH; Chemical Biology, Zentrum für Medizinische Biotechnologie, Universität Duisburg-Essen, Universitätsstrasse 2, 45117, Essen, Germany.
  • Liu Y; Chemical Biology, Zentrum für Medizinische Biotechnologie, Universität Duisburg-Essen, Universitätsstrasse 2, 45117, Essen, Germany.
  • Xiong Y; Basic Forestry and Proteomics Research Center, Haixia Institute of Science and Technology, Fujian Agriculture and Forestry University, Fujian Province, 350002, P.R. China.
  • Schlicht M; Basic Forestry and Proteomics Research Center, Haixia Institute of Science and Technology, Fujian Agriculture and Forestry University, Fujian Province, 350002, P.R. China.
  • Schillinger J; Chemical Biology Laboratory, Max-Planck-Institute for Plant Breeding Research, Carl-von-Linnè-Weg 10, 50829, Köln, Germany.
  • Kracher B; Microbiology, Zentrum für Medizinische Biotechnologie, Universität Duisburg-Essen, Universitätsstrasse 2, 45117, Essen, Germany.
  • Ehrmann M; Bioinformatics, Department of Plant Microbe Interactions, Max-Planck-Institute for Plant Breeding Research, Carl-von-Linnè-Weg 10, 50829, Köln, Germany.
  • Kombrink E; Microbiology, Zentrum für Medizinische Biotechnologie, Universität Duisburg-Essen, Universitätsstrasse 2, 45117, Essen, Germany.
  • Kaschani F; Chemical Biology Laboratory, Max-Planck-Institute for Plant Breeding Research, Carl-von-Linnè-Weg 10, 50829, Köln, Germany.
  • Kaiser M; Chemical Biology, Zentrum für Medizinische Biotechnologie, Universität Duisburg-Essen, Universitätsstrasse 2, 45117, Essen, Germany.
Chemistry ; 24(48): 12500-12504, 2018 Aug 27.
Article em En | MEDLINE | ID: mdl-29932252
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oligopeptídeos / Inibidores de Proteínas Quinases / Serina-Treonina Quinases TOR Tipo de estudo: Diagnostic_studies / Prognostic_studies Idioma: En Revista: Chemistry Assunto da revista: QUIMICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oligopeptídeos / Inibidores de Proteínas Quinases / Serina-Treonina Quinases TOR Tipo de estudo: Diagnostic_studies / Prognostic_studies Idioma: En Revista: Chemistry Assunto da revista: QUIMICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha