Longitudinal evaluation of ventricular volume changes associated with mild traumatic brain injury in military service members.
Brain Inj
; 32(10): 1245-1255, 2018.
Article
em En
| MEDLINE
| ID: mdl-29985658
ABSTRACT
PRIMARY OBJECTIVE:
To investigate differences in longitudinal trajectories of ventricle-brain ratio (VBR), a general measure of brain atrophy, between Veterans with and without history of mild traumatic brain injury (mTBI). RESEARCHDESIGN:
Structural magnetic resonance imaging (MRI) was used to calculate VBR in 70 Veterans with a history of mTBI and 34 Veterans without such history at two time points approximately 3 and 8 years after a combat deployment. MAIN OUTCOMES ANDRESULTS:
Both groups demonstrated a quadratic relationship between VBR and age that is consistent with normal developmental trajectories. Veterans with history of mTBI had larger total brain volume, but no interaction between mTBI and age was observed for brain volume, ventricular volume, or VBR.CONCLUSIONS:
In our longitudinal sample of deployed Veterans, mTBI was not associated with gross brain atrophy as reflected by abnormally high VBR or abnormal increases in VBR over time.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Encéfalo
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Concussão Encefálica
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Ventrículos Cerebrais
Tipo de estudo:
Etiology_studies
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Evaluation_studies
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Incidence_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Adult
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Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Brain Inj
Assunto da revista:
CEREBRO
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Estados Unidos